TY  - JOUR
AU  - Matija, Lidija
AU  - Stanković, Ivana
AU  - Purić, Milica
AU  - Miličić, Milica
AU  - Maksimović-Ivanić, Danijela
AU  - Mijatović, Sanja
AU  - Krajnović, Tamara
AU  - Gordić, Vuk
AU  - Koruga, Đuro
PY  - 2023
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/7203
AB  - The human body contains 60–70% water, depending on age. As a body fluid, it is not only a medium in which physical and chemical processes take place, but it is also one of the active mediators. Water is the richest substance with non-covalent hydrogen bonds. Water molecules, by themselves (in vacuum), are diamagnetic but when organized into clusters, they become diamagnetic or paramagnetic. Also, biomolecules (DNA, collagen, clathrin, and other proteins) have non-covalent hydrogen bonds in their structure. The interaction, as well as signal transmission, between water and biomolecules is achieved through the vibrations of covalent and non-covalent hydrogen bonds, which determine the state and dynamics of conformational changes in biomolecules. Disruptive conformational changes in biomolecules, cells, and tissues lead to their dysfunctionality, so they are a frequent cause of many disorders and diseases. For example, the rearrangement of hydrogen bonding due to mitochondrial disease mutation in cytochrome bc1 disturbs heme bH redox potential and spin state. In order to prevent and repair the dysfunctional conformational changes, a liquid substance was developed based on the second derivative of the C60 molecule (SD-C60), which has classical and quantum properties. The characterization of SD-C60 by UV-VIS-NIR, FTIR, TEM, and AFM/MFM was performed and it is shown that SD-C60 water layers generate vibrations with near-zero phase dispersion which are transmitted through Fibonacci’s water chains to biomolecules. In comparison with previously published SD-C60 derivate (3HFWC, size until 10 nm, and 1–5 water layers), the improved formulation (3HFWC-W, size 10–25 nm, and 6–9 water layers) showed multiplied cytotoxic activity against melanoma cell lines of different aggressiveness. Apart from this, the mode of action was preserved and based on an induction of senescence rather than cell death. Importantly, high selectivity towards malignant phenotypes was detected. Observed effects can be ascribed to a machinery of hydrogen bonds, which are generated in SD-C60 and transmitted through water to biomolecules. This approach may open a new field in science and healthcare—a “water-based nanomedicine”.
PB  - MDPI
T2  - Micromachines
T1  - The Second Derivative of Fullerene C60 (SD-C60) and Biomolecular Machinery of Hydrogen Bonds: Water-Based Nanomedicine
IS  - 14
SP  - 2152
DO  - 10.3390/mi14122152
ER  - 

@article{
author = "Matija, Lidija and Stanković, Ivana and Purić, Milica and Miličić, Milica and Maksimović-Ivanić, Danijela and Mijatović, Sanja and Krajnović, Tamara and Gordić, Vuk and Koruga, Đuro",
year = "2023",
abstract = "The human body contains 60–70% water, depending on age. As a body fluid, it is not only a medium in which physical and chemical processes take place, but it is also one of the active mediators. Water is the richest substance with non-covalent hydrogen bonds. Water molecules, by themselves (in vacuum), are diamagnetic but when organized into clusters, they become diamagnetic or paramagnetic. Also, biomolecules (DNA, collagen, clathrin, and other proteins) have non-covalent hydrogen bonds in their structure. The interaction, as well as signal transmission, between water and biomolecules is achieved through the vibrations of covalent and non-covalent hydrogen bonds, which determine the state and dynamics of conformational changes in biomolecules. Disruptive conformational changes in biomolecules, cells, and tissues lead to their dysfunctionality, so they are a frequent cause of many disorders and diseases. For example, the rearrangement of hydrogen bonding due to mitochondrial disease mutation in cytochrome bc1 disturbs heme bH redox potential and spin state. In order to prevent and repair the dysfunctional conformational changes, a liquid substance was developed based on the second derivative of the C60 molecule (SD-C60), which has classical and quantum properties. The characterization of SD-C60 by UV-VIS-NIR, FTIR, TEM, and AFM/MFM was performed and it is shown that SD-C60 water layers generate vibrations with near-zero phase dispersion which are transmitted through Fibonacci’s water chains to biomolecules. In comparison with previously published SD-C60 derivate (3HFWC, size until 10 nm, and 1–5 water layers), the improved formulation (3HFWC-W, size 10–25 nm, and 6–9 water layers) showed multiplied cytotoxic activity against melanoma cell lines of different aggressiveness. Apart from this, the mode of action was preserved and based on an induction of senescence rather than cell death. Importantly, high selectivity towards malignant phenotypes was detected. Observed effects can be ascribed to a machinery of hydrogen bonds, which are generated in SD-C60 and transmitted through water to biomolecules. This approach may open a new field in science and healthcare—a “water-based nanomedicine”.",
publisher = "MDPI",
journal = "Micromachines",
title = "The Second Derivative of Fullerene C60 (SD-C60) and Biomolecular Machinery of Hydrogen Bonds: Water-Based Nanomedicine",
number = "14",
pages = "2152",
doi = "10.3390/mi14122152"
}

Matija, L., Stanković, I., Purić, M., Miličić, M., Maksimović-Ivanić, D., Mijatović, S., Krajnović, T., Gordić, V.,& Koruga, Đ.. (2023). The Second Derivative of Fullerene C60 (SD-C60) and Biomolecular Machinery of Hydrogen Bonds: Water-Based Nanomedicine. in Micromachines
MDPI.(14), 2152.
https://doi.org/10.3390/mi14122152

Matija L, Stanković I, Purić M, Miličić M, Maksimović-Ivanić D, Mijatović S, Krajnović T, Gordić V, Koruga Đ. The Second Derivative of Fullerene C60 (SD-C60) and Biomolecular Machinery of Hydrogen Bonds: Water-Based Nanomedicine. in Micromachines. 2023;(14):2152.
doi:10.3390/mi14122152 .

Matija, Lidija, Stanković, Ivana, Purić, Milica, Miličić, Milica, Maksimović-Ivanić, Danijela, Mijatović, Sanja, Krajnović, Tamara, Gordić, Vuk, Koruga, Đuro, "The Second Derivative of Fullerene C60 (SD-C60) and Biomolecular Machinery of Hydrogen Bonds: Water-Based Nanomedicine" in Micromachines, no. 14 (2023):2152,
https://doi.org/10.3390/mi14122152 . .

TY  - CONF
AU  - Jeftić, Branislava
AU  - Hut, Igor
AU  - Stanković, Ivana
AU  - Šakota Rosić, Jovana
AU  - Matija, Lidija
AU  - Koruga, Đuro
PY  - 2022
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/4849
AB  - In order to further investigate performance of Optomagnetic Imaging Spectroscopy in cervical cancer detection, deep learning algorithm has been used for classification of optomagnetic spectra of the samples. Optomagnetic spectra reflect cell properties and based on those properties it is possible to differ-entiate normal cells from cells showing different levels of dysplasia and cancer cells. In one of the previous research, Optomagnetic imaging spectroscopy has demonstrated high percentages of accuracy, sensitivity and specificity in cervical cancer detection, particularly in the case of binary classification. Somewhat lower accuracy percentages were obtained in the case of four class classification. Compared to the results obtained by conventional machine learning classification algorithms, proposed deep learning algorithm achieves similar accuracy results (80%), greater sensitivity (83.3%), and comparable specificity percentages (78%).
C3  - Contemporary Materials
T1  - Deep learning algorithm for cervical cancer detection based on images of optomagnetic spectra
EP  - 184
IS  - 2
SP  - 178
VL  - 13
DO  - 10.7251/COMEN2202178J
ER  - 

@conference{
author = "Jeftić, Branislava and Hut, Igor and Stanković, Ivana and Šakota Rosić, Jovana and Matija, Lidija and Koruga, Đuro",
year = "2022",
abstract = "In order to further investigate performance of Optomagnetic Imaging Spectroscopy in cervical cancer detection, deep learning algorithm has been used for classification of optomagnetic spectra of the samples. Optomagnetic spectra reflect cell properties and based on those properties it is possible to differ-entiate normal cells from cells showing different levels of dysplasia and cancer cells. In one of the previous research, Optomagnetic imaging spectroscopy has demonstrated high percentages of accuracy, sensitivity and specificity in cervical cancer detection, particularly in the case of binary classification. Somewhat lower accuracy percentages were obtained in the case of four class classification. Compared to the results obtained by conventional machine learning classification algorithms, proposed deep learning algorithm achieves similar accuracy results (80%), greater sensitivity (83.3%), and comparable specificity percentages (78%).",
journal = "Contemporary Materials",
title = "Deep learning algorithm for cervical cancer detection based on images of optomagnetic spectra",
pages = "184-178",
number = "2",
volume = "13",
doi = "10.7251/COMEN2202178J"
}

Jeftić, B., Hut, I., Stanković, I., Šakota Rosić, J., Matija, L.,& Koruga, Đ.. (2022). Deep learning algorithm for cervical cancer detection based on images of optomagnetic spectra. in Contemporary Materials, 13(2), 178-184.
https://doi.org/10.7251/COMEN2202178J

Jeftić B, Hut I, Stanković I, Šakota Rosić J, Matija L, Koruga Đ. Deep learning algorithm for cervical cancer detection based on images of optomagnetic spectra. in Contemporary Materials. 2022;13(2):178-184.
doi:10.7251/COMEN2202178J .

Jeftić, Branislava, Hut, Igor, Stanković, Ivana, Šakota Rosić, Jovana, Matija, Lidija, Koruga, Đuro, "Deep learning algorithm for cervical cancer detection based on images of optomagnetic spectra" in Contemporary Materials, 13, no. 2 (2022):178-184,
https://doi.org/10.7251/COMEN2202178J . .

TY  - JOUR
AU  - Rudolf, Rebeka
AU  - Jelen, Z.
AU  - Zadravec, M.
AU  - Majerić, P.
AU  - Jović, Zorana
AU  - Vuksanović, M.
AU  - Stanković, Ivana
AU  - Matija, Lidija
AU  - Dragičević, Aleksandra
AU  - Thompson, Miso N.
AU  - Horvat, A.
AU  - Koruga, Đuro
PY  - 2022
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3772
AB  - Three types of gold nanoparticles (AuNPs) were synthesised with a custom-made Ultrasonic Spray Pyrolysis (USP) device, from aqueous solutions of gold (III) chloride (AuCl3) and gold (III) acetate (AuC6H12O6), with an initial concentration of Au 0.5 g/L. AuNPs were collected in suspensions of deionised (D.I.) water with the stabilisers polyvinylpyrrolidone (PVP) or polyethylene glycol (PEG), followed by the process of freeze drying the AuNPs to be useful as a new additive for the cream. The standard cream base was used as a matrix for preparation of three types of cream with AuNPs in the same concentration ratios. The third AuNPs cream was prepared with a patented hydroxylated fullerene water complex (3HFWC-W) matrix. To examine the effect of AuNPs as additive in creams, a six-week study of test creams was conducted on 33 volunteers with no dermatological diseases. During the study three main parameters of the skin where measured: Collagen quality, skin moisturisation and the epidermis-dermis function. The results of the study found improvements of collagen quality between 18-24 %, achieved due to the use of AuNPs in standard creams, while the cream with the combination of 3HFWC-W and AuNPs gave significantly higher improvements with a value of 45.7 %. It was also discovered that hydration of the skin (stratum cornum) increased by 6.4-9.6 % in standard creams with AuNPs, and 73.7 % in the 3HFWC/AuNPs' cream. Similar results were measured by the epidermisdermis function, where 24-28 % improvement for standard creams with AuNPs was identified, and 38.4 % for the cream 3HFWC-W/AuNPs.
PB  - Univ Maribor, Fac Mechanical Engineering, Maribor
T2  - Advances in Production Engineering & Management
T1  - A gold nanoparticles and hydroxylated fullerene water complex as a new product for cosmetics
EP  - 107
IS  - 1
SP  - 89
VL  - 17
DO  - 10.14743/apem2022.1.423
ER  - 

@article{
author = "Rudolf, Rebeka and Jelen, Z. and Zadravec, M. and Majerić, P. and Jović, Zorana and Vuksanović, M. and Stanković, Ivana and Matija, Lidija and Dragičević, Aleksandra and Thompson, Miso N. and Horvat, A. and Koruga, Đuro",
year = "2022",
abstract = "Three types of gold nanoparticles (AuNPs) were synthesised with a custom-made Ultrasonic Spray Pyrolysis (USP) device, from aqueous solutions of gold (III) chloride (AuCl3) and gold (III) acetate (AuC6H12O6), with an initial concentration of Au 0.5 g/L. AuNPs were collected in suspensions of deionised (D.I.) water with the stabilisers polyvinylpyrrolidone (PVP) or polyethylene glycol (PEG), followed by the process of freeze drying the AuNPs to be useful as a new additive for the cream. The standard cream base was used as a matrix for preparation of three types of cream with AuNPs in the same concentration ratios. The third AuNPs cream was prepared with a patented hydroxylated fullerene water complex (3HFWC-W) matrix. To examine the effect of AuNPs as additive in creams, a six-week study of test creams was conducted on 33 volunteers with no dermatological diseases. During the study three main parameters of the skin where measured: Collagen quality, skin moisturisation and the epidermis-dermis function. The results of the study found improvements of collagen quality between 18-24 %, achieved due to the use of AuNPs in standard creams, while the cream with the combination of 3HFWC-W and AuNPs gave significantly higher improvements with a value of 45.7 %. It was also discovered that hydration of the skin (stratum cornum) increased by 6.4-9.6 % in standard creams with AuNPs, and 73.7 % in the 3HFWC/AuNPs' cream. Similar results were measured by the epidermisdermis function, where 24-28 % improvement for standard creams with AuNPs was identified, and 38.4 % for the cream 3HFWC-W/AuNPs.",
publisher = "Univ Maribor, Fac Mechanical Engineering, Maribor",
journal = "Advances in Production Engineering & Management",
title = "A gold nanoparticles and hydroxylated fullerene water complex as a new product for cosmetics",
pages = "107-89",
number = "1",
volume = "17",
doi = "10.14743/apem2022.1.423"
}

Rudolf, R., Jelen, Z., Zadravec, M., Majerić, P., Jović, Z., Vuksanović, M., Stanković, I., Matija, L., Dragičević, A., Thompson, M. N., Horvat, A.,& Koruga, Đ.. (2022). A gold nanoparticles and hydroxylated fullerene water complex as a new product for cosmetics. in Advances in Production Engineering & Management
Univ Maribor, Fac Mechanical Engineering, Maribor., 17(1), 89-107.
https://doi.org/10.14743/apem2022.1.423

Rudolf R, Jelen Z, Zadravec M, Majerić P, Jović Z, Vuksanović M, Stanković I, Matija L, Dragičević A, Thompson MN, Horvat A, Koruga Đ. A gold nanoparticles and hydroxylated fullerene water complex as a new product for cosmetics. in Advances in Production Engineering & Management. 2022;17(1):89-107.
doi:10.14743/apem2022.1.423 .

Rudolf, Rebeka, Jelen, Z., Zadravec, M., Majerić, P., Jović, Zorana, Vuksanović, M., Stanković, Ivana, Matija, Lidija, Dragičević, Aleksandra, Thompson, Miso N., Horvat, A., Koruga, Đuro, "A gold nanoparticles and hydroxylated fullerene water complex as a new product for cosmetics" in Advances in Production Engineering & Management, 17, no. 1 (2022):89-107,
https://doi.org/10.14743/apem2022.1.423 . .

TY  - CONF
AU  - Draca, Dijana
AU  - Markelić, Milica
AU  - Mojić, Marija
AU  - Jelaca, Sanja
AU  - Mijatović, Sanja
AU  - Jović, Zorana
AU  - Dragičević, Aleksandra
AU  - Koruga, Đuro
AU  - Maksimović-Ivanić, Danijela
PY  - 2021
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3488
PB  - Wiley, Hoboken
C3  - European Journal of Immunology
T1  - Anti-melanoma effects of Hyper-harmonized hydroxylated fullerene water complex and hyperpolarized light in vivo
EP  - 353
SP  - 353
VL  - 51
UR  - https://hdl.handle.net/21.15107/rcub_machinery_3488
ER  - 

@conference{
author = "Draca, Dijana and Markelić, Milica and Mojić, Marija and Jelaca, Sanja and Mijatović, Sanja and Jović, Zorana and Dragičević, Aleksandra and Koruga, Đuro and Maksimović-Ivanić, Danijela",
year = "2021",
publisher = "Wiley, Hoboken",
journal = "European Journal of Immunology",
title = "Anti-melanoma effects of Hyper-harmonized hydroxylated fullerene water complex and hyperpolarized light in vivo",
pages = "353-353",
volume = "51",
url = "https://hdl.handle.net/21.15107/rcub_machinery_3488"
}

Draca, D., Markelić, M., Mojić, M., Jelaca, S., Mijatović, S., Jović, Z., Dragičević, A., Koruga, Đ.,& Maksimović-Ivanić, D.. (2021). Anti-melanoma effects of Hyper-harmonized hydroxylated fullerene water complex and hyperpolarized light in vivo. in European Journal of Immunology
Wiley, Hoboken., 51, 353-353.
https://hdl.handle.net/21.15107/rcub_machinery_3488

Draca D, Markelić M, Mojić M, Jelaca S, Mijatović S, Jović Z, Dragičević A, Koruga Đ, Maksimović-Ivanić D. Anti-melanoma effects of Hyper-harmonized hydroxylated fullerene water complex and hyperpolarized light in vivo. in European Journal of Immunology. 2021;51:353-353.
https://hdl.handle.net/21.15107/rcub_machinery_3488 .

Draca, Dijana, Markelić, Milica, Mojić, Marija, Jelaca, Sanja, Mijatović, Sanja, Jović, Zorana, Dragičević, Aleksandra, Koruga, Đuro, Maksimović-Ivanić, Danijela, "Anti-melanoma effects of Hyper-harmonized hydroxylated fullerene water complex and hyperpolarized light in vivo" in European Journal of Immunology, 51 (2021):353-353,
https://hdl.handle.net/21.15107/rcub_machinery_3488 .

TY  - JOUR
AU  - Miljković, Suzana
AU  - Jeftić, Branislava
AU  - Stanković, Ivana
AU  - Stojiljković, Nikola
AU  - Koruga, Đuro
PY  - 2021
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3625
AB  - Background Hyper Harmonized Hydroxyl Modified Fullerene Substance (3HFWC(+)) establishes hydrogen bonds with the surrounding water molecules and organizes them in clusters with the liquid crystalline state, similar to the properties of water surrounding the biomolecules. Aims To investigate the moisturizing properties of hyperharmonized fullerenol-3HFWC(+) as an emulsion O/W ingredient on the skin. Patients/Methods We have analyzed the reflexion of the blue light from the skin, in vivo, with different levels of moisturization and compared the influence of three groups of cosmetic products (with various active ingredients, 3HFWC(+) or water in same percentage in the "vehiculum") on skin moisturization by measuring paramagnetic/diamagnetic properties by Optomagnetic Imaging Spectroscopy. Results Regenerating Cream and Body Lotion have shown statistically significant increase of diamagnetic features predominantly in all 3 types of creams, while the Hand Cream formulations have not shown statistically significant results after 4 weeks of treatment. Anti-aging cream with 3HFWC(+) demonstrated statistically significant increase of paramagnetic properties of the skin (p(+)/p(-) from 0.90 to 0.62) and showed beneficial effects on information transfer and water content in stratum corneum. Conclusion Although it does not act as a classical moisturizing agent on the skin, 3HFWC(+) can increase moisturization as a result of hydrogen bonds established among 3HFWC(+) and water or biomolecules, liquid crystalline state of water in 3HFWC(+) resembling the properties of water surrounding the biomolecules, and finally, liquid crystalline state of water in the products.
PB  - Wiley, Hoboken
T2  - Journal of Cosmetic Dermatology
T1  - Mechanisms of skin moisturization with hyperharmonized hydroxyl modified fullerene substance
EP  - 3025
IS  - 9
SP  - 3018
VL  - 20
DO  - 10.1111/jocd.13965
ER  - 

@article{
author = "Miljković, Suzana and Jeftić, Branislava and Stanković, Ivana and Stojiljković, Nikola and Koruga, Đuro",
year = "2021",
abstract = "Background Hyper Harmonized Hydroxyl Modified Fullerene Substance (3HFWC(+)) establishes hydrogen bonds with the surrounding water molecules and organizes them in clusters with the liquid crystalline state, similar to the properties of water surrounding the biomolecules. Aims To investigate the moisturizing properties of hyperharmonized fullerenol-3HFWC(+) as an emulsion O/W ingredient on the skin. Patients/Methods We have analyzed the reflexion of the blue light from the skin, in vivo, with different levels of moisturization and compared the influence of three groups of cosmetic products (with various active ingredients, 3HFWC(+) or water in same percentage in the "vehiculum") on skin moisturization by measuring paramagnetic/diamagnetic properties by Optomagnetic Imaging Spectroscopy. Results Regenerating Cream and Body Lotion have shown statistically significant increase of diamagnetic features predominantly in all 3 types of creams, while the Hand Cream formulations have not shown statistically significant results after 4 weeks of treatment. Anti-aging cream with 3HFWC(+) demonstrated statistically significant increase of paramagnetic properties of the skin (p(+)/p(-) from 0.90 to 0.62) and showed beneficial effects on information transfer and water content in stratum corneum. Conclusion Although it does not act as a classical moisturizing agent on the skin, 3HFWC(+) can increase moisturization as a result of hydrogen bonds established among 3HFWC(+) and water or biomolecules, liquid crystalline state of water in 3HFWC(+) resembling the properties of water surrounding the biomolecules, and finally, liquid crystalline state of water in the products.",
publisher = "Wiley, Hoboken",
journal = "Journal of Cosmetic Dermatology",
title = "Mechanisms of skin moisturization with hyperharmonized hydroxyl modified fullerene substance",
pages = "3025-3018",
number = "9",
volume = "20",
doi = "10.1111/jocd.13965"
}

Miljković, S., Jeftić, B., Stanković, I., Stojiljković, N.,& Koruga, Đ.. (2021). Mechanisms of skin moisturization with hyperharmonized hydroxyl modified fullerene substance. in Journal of Cosmetic Dermatology
Wiley, Hoboken., 20(9), 3018-3025.
https://doi.org/10.1111/jocd.13965

Miljković S, Jeftić B, Stanković I, Stojiljković N, Koruga Đ. Mechanisms of skin moisturization with hyperharmonized hydroxyl modified fullerene substance. in Journal of Cosmetic Dermatology. 2021;20(9):3018-3025.
doi:10.1111/jocd.13965 .

Miljković, Suzana, Jeftić, Branislava, Stanković, Ivana, Stojiljković, Nikola, Koruga, Đuro, "Mechanisms of skin moisturization with hyperharmonized hydroxyl modified fullerene substance" in Journal of Cosmetic Dermatology, 20, no. 9 (2021):3018-3025,
https://doi.org/10.1111/jocd.13965 . .

TY  - JOUR
AU  - Lazović, Jelena
AU  - Zopf, Lydia M.
AU  - Hren, Jernej
AU  - Gajdos, Martin
AU  - Slavković, Marija
AU  - Jović, Zorana
AU  - Stanković, Ivana
AU  - Matović, Valentina
AU  - Koruga, Đuro
PY  - 2021
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3541
AB  - The most symmetric molecule, Buckminster fullerene C-60, due to its unique properties, has been intensively studied for various medical and technological advances. Minimally invasive and minimally toxic treatments hold great promise for future applications. With this in mind, this research exploited the physical properties of fullerene molecules for potential therapeutic effects. Pristine fullerenes have peak absorbance in the 380-500 nm range, making them an attractive violet-blue light filter. Since spectral quality of light can affect behavior, this research used resting state functional magnetic resonance imaging (rs fMRI) and behavioral testing to directly evaluate the effects of fullerene-filtered light on brain processing and behavior in mice. The same method was used to study if hydroxyl fullerene water complexes (3HFWC), with or without fullerene-filtered light, modulated brain processing. A month-long, daily exposure to fullerene-filtered light led to decreased activation of the brain area involved in emotional processing (amygdala). Water supplemented with 3HFWC resulted in an activation of brain areas involved in pain modulation and processing (periaqueductal gray), and decreased latency to first reaction when tested with a hot plate. The combination of fullerene-filtered light with 3HFWC in drinking water led to restored sensitivity to a hot plate and activation of brain areas involved in cognitive functions (prelimbic, anterior cingulate and retrosplenial cortex). These results uncovered the potential of fullerene-filtered light to impact emotional processing and modulate pain perception, indicating its further use in stress and pain management.
PB  - MDPI, Basel
T2  - Symmetry
T1  - Fullerene-Filtered Light Spectrum and Fullerenes Modulate Emotional and Pain Processing in Mice
IS  - 11
VL  - 13
DO  - 10.3390/sym13112004
ER  - 

@article{
author = "Lazović, Jelena and Zopf, Lydia M. and Hren, Jernej and Gajdos, Martin and Slavković, Marija and Jović, Zorana and Stanković, Ivana and Matović, Valentina and Koruga, Đuro",
year = "2021",
abstract = "The most symmetric molecule, Buckminster fullerene C-60, due to its unique properties, has been intensively studied for various medical and technological advances. Minimally invasive and minimally toxic treatments hold great promise for future applications. With this in mind, this research exploited the physical properties of fullerene molecules for potential therapeutic effects. Pristine fullerenes have peak absorbance in the 380-500 nm range, making them an attractive violet-blue light filter. Since spectral quality of light can affect behavior, this research used resting state functional magnetic resonance imaging (rs fMRI) and behavioral testing to directly evaluate the effects of fullerene-filtered light on brain processing and behavior in mice. The same method was used to study if hydroxyl fullerene water complexes (3HFWC), with or without fullerene-filtered light, modulated brain processing. A month-long, daily exposure to fullerene-filtered light led to decreased activation of the brain area involved in emotional processing (amygdala). Water supplemented with 3HFWC resulted in an activation of brain areas involved in pain modulation and processing (periaqueductal gray), and decreased latency to first reaction when tested with a hot plate. The combination of fullerene-filtered light with 3HFWC in drinking water led to restored sensitivity to a hot plate and activation of brain areas involved in cognitive functions (prelimbic, anterior cingulate and retrosplenial cortex). These results uncovered the potential of fullerene-filtered light to impact emotional processing and modulate pain perception, indicating its further use in stress and pain management.",
publisher = "MDPI, Basel",
journal = "Symmetry",
title = "Fullerene-Filtered Light Spectrum and Fullerenes Modulate Emotional and Pain Processing in Mice",
number = "11",
volume = "13",
doi = "10.3390/sym13112004"
}

Lazović, J., Zopf, L. M., Hren, J., Gajdos, M., Slavković, M., Jović, Z., Stanković, I., Matović, V.,& Koruga, Đ.. (2021). Fullerene-Filtered Light Spectrum and Fullerenes Modulate Emotional and Pain Processing in Mice. in Symmetry
MDPI, Basel., 13(11).
https://doi.org/10.3390/sym13112004

Lazović J, Zopf LM, Hren J, Gajdos M, Slavković M, Jović Z, Stanković I, Matović V, Koruga Đ. Fullerene-Filtered Light Spectrum and Fullerenes Modulate Emotional and Pain Processing in Mice. in Symmetry. 2021;13(11).
doi:10.3390/sym13112004 .

Lazović, Jelena, Zopf, Lydia M., Hren, Jernej, Gajdos, Martin, Slavković, Marija, Jović, Zorana, Stanković, Ivana, Matović, Valentina, Koruga, Đuro, "Fullerene-Filtered Light Spectrum and Fullerenes Modulate Emotional and Pain Processing in Mice" in Symmetry, 13, no. 11 (2021),
https://doi.org/10.3390/sym13112004 . .

TY  - JOUR
AU  - Jankov, Mirko R.
AU  - Jakšić, Vesna
AU  - Koruga, Đuro
PY  - 2021
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3627
AB  - Uvod/Cilj. Plavo svetlo može da bude štetno za retinu. Nano-materijal od fulerena C60 i polimetil metakrilata (PMMA) transformiše svetlo u harmonizovano hiperpolarizovano svetlo upijajući plavu, ljubičastu i ultraljubičastu talasnu dužinu. Cilj ovog rada bio je da se oceni subjektivni i objektivni uticaj nošenja naočara na obavljanje dnevnih aktivnosti. Metode. Dvadeset pet zdravih dobrovoljaca podvrgnuto je kompletnom oftalmološkom pregledu, ispitivanju kontrastne senzitivnosti (KS) i perimetrije (PM). Popunjavan je upitnik o uticaju naočara na dnevne aktivnosti: dvoje naočara sa različitim koncentracijama fulerena C60 upoređeno je sa dvoje komercijalno dostupnih naočara sa plavim filterom. Rezultati. Nije postojala statistička razlika u KS (p = 0,83), kod PM parametara: MD (mean deviation) (p = 0,36), PSD (pattern standard deviation) (p = 0,25), i kod broja relativnih skotoma (p = 0,31), dok je broj apsolutnih skotoma pokazao statistički značajno smanjenje (p  lt  0,05). Naočare B (sa manjom koncentracijom fulerena od 0,025%) imale su sveukupno najbolju srednju ocenu (p  lt  0,00001): oko četiri petine ispitanika je bolje funkcionisalo danju, dok je oko dve trećine njih osećalo boljitak i danju i noću. Naočare B su isto tako bile superiorne u sveukupnoj oceni zadovoljstva pri svim kombinovanim dnevnim aktivnostima (4,04 ± 1,1) (p = 0,0008). Zaključak. Naočare sa plavim filterom na bazi fulerena C60 povećavaju sveukupan komfor u obavljanju dnevnih aktivnosti pri njihovom nošenju i nakon nošenja. Ovi filteri mogu da budu efikasan način zaštite od očnih bolesti uzrokovanih plavim svetlom uz povećan komfor u obavljanju svakodnevnih aktivnosti.
AB  - Background/Aim. Blue light might be harmful to the retina. The nano-material based on fullerene C60 and polymethyl methacrylate (PMMA) transforms the light into harmonized light and absorbs violet, blue, and ultraviolet (UV) wavelength. The aim of the study was to evaluate the subjective and objective impact of the spectacles on daily activities. Methods. Twenty-five healthy participants were submitted to contrast sensitivity (CS) and visual field (VF) testing and a questionnaire about the influence of spectacles on daily activities: two spectacles with different concentrations of fullerene C60 vs. two commercially available blue-blocking spectacles. Results. There was no statistical difference in CS (p = 0.83), in VF parameters: mean deviation (MD) (p = 0.36), pattern standard deviation (PSD) (p = 0.25), number of relative scotomas (p = 0.31), while the number of absolute scotomas showed a statistically significant decrease (p  lt  0.05). Spectacles B (with a lower concentration of fullerene - 0.025%) had the best overall comfort mean score (p  lt  0.00001): four-fifths of participants performed better only during the day, while two-thirds performed better both during the day and night. Spectacles B were also superior in overall satisfaction regarding all combined daily activities (4.04 ± 1.1) (p = 0.0008). Conclusion. Blue-blocking filters with fullerene C60 increase the overall comfort of daily tasks during and after their use. These filters might be an effective mechanism that can protect us from ocular pathologies while providing better comfort in daily activities.
PB  - Vojnomedicinska akademija - Institut za naučne informacije, Beograd
T2  - Vojnosanitetski Pregled
T1  - Klinički efekat nanofotonskih naočara s plavim filterom na bazi fulerena C60 i polimetil metakrilata (PMMA)
T1  - Clinical impact of nanophotonic blue-light filtering spectacles based on fullerene C60 and polymethyl methacrylate (PMMA)
EP  - 408
IS  - 4
SP  - 403
VL  - 78
DO  - 10.2298/VSP190522082J
ER  - 

@article{
author = "Jankov, Mirko R. and Jakšić, Vesna and Koruga, Đuro",
year = "2021",
abstract = "Uvod/Cilj. Plavo svetlo može da bude štetno za retinu. Nano-materijal od fulerena C60 i polimetil metakrilata (PMMA) transformiše svetlo u harmonizovano hiperpolarizovano svetlo upijajući plavu, ljubičastu i ultraljubičastu talasnu dužinu. Cilj ovog rada bio je da se oceni subjektivni i objektivni uticaj nošenja naočara na obavljanje dnevnih aktivnosti. Metode. Dvadeset pet zdravih dobrovoljaca podvrgnuto je kompletnom oftalmološkom pregledu, ispitivanju kontrastne senzitivnosti (KS) i perimetrije (PM). Popunjavan je upitnik o uticaju naočara na dnevne aktivnosti: dvoje naočara sa različitim koncentracijama fulerena C60 upoređeno je sa dvoje komercijalno dostupnih naočara sa plavim filterom. Rezultati. Nije postojala statistička razlika u KS (p = 0,83), kod PM parametara: MD (mean deviation) (p = 0,36), PSD (pattern standard deviation) (p = 0,25), i kod broja relativnih skotoma (p = 0,31), dok je broj apsolutnih skotoma pokazao statistički značajno smanjenje (p  lt  0,05). Naočare B (sa manjom koncentracijom fulerena od 0,025%) imale su sveukupno najbolju srednju ocenu (p  lt  0,00001): oko četiri petine ispitanika je bolje funkcionisalo danju, dok je oko dve trećine njih osećalo boljitak i danju i noću. Naočare B su isto tako bile superiorne u sveukupnoj oceni zadovoljstva pri svim kombinovanim dnevnim aktivnostima (4,04 ± 1,1) (p = 0,0008). Zaključak. Naočare sa plavim filterom na bazi fulerena C60 povećavaju sveukupan komfor u obavljanju dnevnih aktivnosti pri njihovom nošenju i nakon nošenja. Ovi filteri mogu da budu efikasan način zaštite od očnih bolesti uzrokovanih plavim svetlom uz povećan komfor u obavljanju svakodnevnih aktivnosti., Background/Aim. Blue light might be harmful to the retina. The nano-material based on fullerene C60 and polymethyl methacrylate (PMMA) transforms the light into harmonized light and absorbs violet, blue, and ultraviolet (UV) wavelength. The aim of the study was to evaluate the subjective and objective impact of the spectacles on daily activities. Methods. Twenty-five healthy participants were submitted to contrast sensitivity (CS) and visual field (VF) testing and a questionnaire about the influence of spectacles on daily activities: two spectacles with different concentrations of fullerene C60 vs. two commercially available blue-blocking spectacles. Results. There was no statistical difference in CS (p = 0.83), in VF parameters: mean deviation (MD) (p = 0.36), pattern standard deviation (PSD) (p = 0.25), number of relative scotomas (p = 0.31), while the number of absolute scotomas showed a statistically significant decrease (p  lt  0.05). Spectacles B (with a lower concentration of fullerene - 0.025%) had the best overall comfort mean score (p  lt  0.00001): four-fifths of participants performed better only during the day, while two-thirds performed better both during the day and night. Spectacles B were also superior in overall satisfaction regarding all combined daily activities (4.04 ± 1.1) (p = 0.0008). Conclusion. Blue-blocking filters with fullerene C60 increase the overall comfort of daily tasks during and after their use. These filters might be an effective mechanism that can protect us from ocular pathologies while providing better comfort in daily activities.",
publisher = "Vojnomedicinska akademija - Institut za naučne informacije, Beograd",
journal = "Vojnosanitetski Pregled",
title = "Klinički efekat nanofotonskih naočara s plavim filterom na bazi fulerena C60 i polimetil metakrilata (PMMA), Clinical impact of nanophotonic blue-light filtering spectacles based on fullerene C60 and polymethyl methacrylate (PMMA)",
pages = "408-403",
number = "4",
volume = "78",
doi = "10.2298/VSP190522082J"
}

Jankov, M. R., Jakšić, V.,& Koruga, Đ.. (2021). Klinički efekat nanofotonskih naočara s plavim filterom na bazi fulerena C60 i polimetil metakrilata (PMMA). in Vojnosanitetski Pregled
Vojnomedicinska akademija - Institut za naučne informacije, Beograd., 78(4), 403-408.
https://doi.org/10.2298/VSP190522082J

Jankov MR, Jakšić V, Koruga Đ. Klinički efekat nanofotonskih naočara s plavim filterom na bazi fulerena C60 i polimetil metakrilata (PMMA). in Vojnosanitetski Pregled. 2021;78(4):403-408.
doi:10.2298/VSP190522082J .

Jankov, Mirko R., Jakšić, Vesna, Koruga, Đuro, "Klinički efekat nanofotonskih naočara s plavim filterom na bazi fulerena C60 i polimetil metakrilata (PMMA)" in Vojnosanitetski Pregled, 78, no. 4 (2021):403-408,
https://doi.org/10.2298/VSP190522082J . .

TY  - CONF
AU  - Matija, Lidija
AU  - Kosić, Boris
AU  - Jeftić, Branislava
AU  - Stanković, Ivana
AU  - Koruga, Đuro
PY  - 2020
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/5613
AB  - In this paper geometry and design in material science and engineering, which have been an
inspiration from nature and biology is investigated. It is found out that symmetry, harmony, and
perfection play crucial rule in this mimicry. In the symmetry approach not only symmetry of the
crystallography group is included, but also molecular symmetry groups, Kugel and Curie symmetry
groups. The criteria of harmony are based on Fibonacci sequences and Fibonacci numbers Φ,-Φ,φ,-
φ. Symmetry and harmony are giving beauty to geometry and design in nature, biology, and
engineering. However, in this investigation, perfection is also included (based on the perfect
numbers) that gives, besides beauty, a new property of “sublime” to the objects and processes.
In this paper, a few examples of mimicry in relation to nature-biology-engineering based
on symmetry, harmony, and perfection are presented. One of the examples of that kind of mimicry is
a spiral galaxy- centrioles-solar plants. The second one is molecule C60 in space (in cosmic dust),
clathrin in the human brain, and C60 in nanophotonics, nanocosmetics, and medicine. However,
more examples of biomimicry (from biology to engineering) are presented. One of the more
interesting examples is a container for cosmetically use with complex geometry and design based on
the pentagonal-hexagonal organization of collagen in human tissue.
According to our investigation, we can conclude that optimization of mass-energy, energyinformation,
and information-control (regulation) in the nature, biology, and engineering are
principle which determinate geometry and design of objects.
C3  - THE 7TH ICGG CONFERENCE MONGEOMETRIJA 2020, Proceedings, Belgrade: 18-21 September 2020
T1  - Mimicry of Geometry and Design from the Nature and Biology to Material Science and Engineering
EP  - 259
SP  - 251
UR  - https://hdl.handle.net/21.15107/rcub_machinery_5613
ER  - 

@conference{
author = "Matija, Lidija and Kosić, Boris and Jeftić, Branislava and Stanković, Ivana and Koruga, Đuro",
year = "2020",
abstract = "In this paper geometry and design in material science and engineering, which have been an
inspiration from nature and biology is investigated. It is found out that symmetry, harmony, and
perfection play crucial rule in this mimicry. In the symmetry approach not only symmetry of the
crystallography group is included, but also molecular symmetry groups, Kugel and Curie symmetry
groups. The criteria of harmony are based on Fibonacci sequences and Fibonacci numbers Φ,-Φ,φ,-
φ. Symmetry and harmony are giving beauty to geometry and design in nature, biology, and
engineering. However, in this investigation, perfection is also included (based on the perfect
numbers) that gives, besides beauty, a new property of “sublime” to the objects and processes.
In this paper, a few examples of mimicry in relation to nature-biology-engineering based
on symmetry, harmony, and perfection are presented. One of the examples of that kind of mimicry is
a spiral galaxy- centrioles-solar plants. The second one is molecule C60 in space (in cosmic dust),
clathrin in the human brain, and C60 in nanophotonics, nanocosmetics, and medicine. However,
more examples of biomimicry (from biology to engineering) are presented. One of the more
interesting examples is a container for cosmetically use with complex geometry and design based on
the pentagonal-hexagonal organization of collagen in human tissue.
According to our investigation, we can conclude that optimization of mass-energy, energyinformation,
and information-control (regulation) in the nature, biology, and engineering are
principle which determinate geometry and design of objects.",
journal = "THE 7TH ICGG CONFERENCE MONGEOMETRIJA 2020, Proceedings, Belgrade: 18-21 September 2020",
title = "Mimicry of Geometry and Design from the Nature and Biology to Material Science and Engineering",
pages = "259-251",
url = "https://hdl.handle.net/21.15107/rcub_machinery_5613"
}

Matija, L., Kosić, B., Jeftić, B., Stanković, I.,& Koruga, Đ.. (2020). Mimicry of Geometry and Design from the Nature and Biology to Material Science and Engineering. in THE 7TH ICGG CONFERENCE MONGEOMETRIJA 2020, Proceedings, Belgrade: 18-21 September 2020, 251-259.
https://hdl.handle.net/21.15107/rcub_machinery_5613

Matija L, Kosić B, Jeftić B, Stanković I, Koruga Đ. Mimicry of Geometry and Design from the Nature and Biology to Material Science and Engineering. in THE 7TH ICGG CONFERENCE MONGEOMETRIJA 2020, Proceedings, Belgrade: 18-21 September 2020. 2020;:251-259.
https://hdl.handle.net/21.15107/rcub_machinery_5613 .

Matija, Lidija, Kosić, Boris, Jeftić, Branislava, Stanković, Ivana, Koruga, Đuro, "Mimicry of Geometry and Design from the Nature and Biology to Material Science and Engineering" in THE 7TH ICGG CONFERENCE MONGEOMETRIJA 2020, Proceedings, Belgrade: 18-21 September 2020 (2020):251-259,
https://hdl.handle.net/21.15107/rcub_machinery_5613 .

TY  - JOUR
AU  - Stanković, Ivana
AU  - Matija, Lidija
AU  - Jankov, M.
AU  - Jeftić, Branislava
AU  - Koruga, I.
AU  - Koruga, Đuro
PY  - 2020
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3382
AB  - Poly(methyl methacrylate)-Fullerene (PMMA/C-60) nanocomposites, with different concentrations of C(60)molecules (0.025 wt.%, 0.05 wt.%, 0.075 wt.% and 0.1 wt.%), were synthesized and characterized by Magnetic Force Microscopy and UV-VIS spectroscopy. Characterization had two main objectives: to identify C(60)molecules in the PMMA/C(60)complex and to evaluate the order of PMMA and C(60)molecules in it. Since the structural properties of PMMA/C(60)complex depend on the arrangement of methyl methacrylate (MMA) and C(60)molecules, it can be concluded that the structure of the complex directly correlates to the ratio of an unpaired/paired electrons within the material. To investigate the influence of different concentrations of fullerene molecules in PMMA on the attraction and the repulsion forces in material, based on paired and unpaired electrons, and ultimately on the complex structural and optical properties, Magnetic Force Microscopy was used. Investigation showed that PMMA/C(60)complex with 0.025 wt.% concentration of C(60)has the best structural and optical properties for applications in ophthalmology, and may be used as a new material for spectacles. UV-VIS Spectroscopic analysis in domain of 380 to780 nm showed that PMMA material with 0.025 wt.% concentration of C(60)reduces UV and high blue energy light for more than 60% and in new spectral scenario ratio of blue and green spectra is changed.
PB  - Springer, Dordrecht
T2  - Journal of Polymer Research
T1  - Optical and structural properties of PMMA/C(60)composites with different concentrations of C(60)molecules and its possible applications
IS  - 8
VL  - 27
DO  - 10.1007/s10965-020-02203-4
ER  - 

@article{
author = "Stanković, Ivana and Matija, Lidija and Jankov, M. and Jeftić, Branislava and Koruga, I. and Koruga, Đuro",
year = "2020",
abstract = "Poly(methyl methacrylate)-Fullerene (PMMA/C-60) nanocomposites, with different concentrations of C(60)molecules (0.025 wt.%, 0.05 wt.%, 0.075 wt.% and 0.1 wt.%), were synthesized and characterized by Magnetic Force Microscopy and UV-VIS spectroscopy. Characterization had two main objectives: to identify C(60)molecules in the PMMA/C(60)complex and to evaluate the order of PMMA and C(60)molecules in it. Since the structural properties of PMMA/C(60)complex depend on the arrangement of methyl methacrylate (MMA) and C(60)molecules, it can be concluded that the structure of the complex directly correlates to the ratio of an unpaired/paired electrons within the material. To investigate the influence of different concentrations of fullerene molecules in PMMA on the attraction and the repulsion forces in material, based on paired and unpaired electrons, and ultimately on the complex structural and optical properties, Magnetic Force Microscopy was used. Investigation showed that PMMA/C(60)complex with 0.025 wt.% concentration of C(60)has the best structural and optical properties for applications in ophthalmology, and may be used as a new material for spectacles. UV-VIS Spectroscopic analysis in domain of 380 to780 nm showed that PMMA material with 0.025 wt.% concentration of C(60)reduces UV and high blue energy light for more than 60% and in new spectral scenario ratio of blue and green spectra is changed.",
publisher = "Springer, Dordrecht",
journal = "Journal of Polymer Research",
title = "Optical and structural properties of PMMA/C(60)composites with different concentrations of C(60)molecules and its possible applications",
number = "8",
volume = "27",
doi = "10.1007/s10965-020-02203-4"
}

Stanković, I., Matija, L., Jankov, M., Jeftić, B., Koruga, I.,& Koruga, Đ.. (2020). Optical and structural properties of PMMA/C(60)composites with different concentrations of C(60)molecules and its possible applications. in Journal of Polymer Research
Springer, Dordrecht., 27(8).
https://doi.org/10.1007/s10965-020-02203-4

Stanković I, Matija L, Jankov M, Jeftić B, Koruga I, Koruga Đ. Optical and structural properties of PMMA/C(60)composites with different concentrations of C(60)molecules and its possible applications. in Journal of Polymer Research. 2020;27(8).
doi:10.1007/s10965-020-02203-4 .

Stanković, Ivana, Matija, Lidija, Jankov, M., Jeftić, Branislava, Koruga, I., Koruga, Đuro, "Optical and structural properties of PMMA/C(60)composites with different concentrations of C(60)molecules and its possible applications" in Journal of Polymer Research, 27, no. 8 (2020),
https://doi.org/10.1007/s10965-020-02203-4 . .

TY  - JOUR
AU  - Miljković, Suzana
AU  - Jeftić, Branislava
AU  - Šarac, Dušan
AU  - Matović, Valentina
AU  - Slavković, Marija
AU  - Koruga, Đuro
PY  - 2020
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3343
AB  - Background Fullerene water complex establishes the optimal order and function of biomolecules in natural, biophysical way by transducing the signal through water hydrogen bonds to biomolecules. Objectives This paper considers the effects of the patented hyper-harmonized-hydroxylated fullerene water complex (3HFWC) on biophysical properties of the skin collagen molecules. Method Optomagnetic imaging spectroscopy (OMIS) has been used for the analysis of the biophysical skin properties (diamagnetic/paramagnetic) after applying three groups of different cosmetic products. Tested cosmetic products were prepared by replacing the active ingredients with 3HFWC or with water in four commercial products. The original commercial creams and their vehiculums with water added served as control groups. Data were statistically analyzed using paired t test in R software. Results t Test gave statistically significant results for all of the products with 3HFWC, while within the control group, only body lotion and hand cream did show statistically significant results (P  lt  0.05). Significant improvements in abundance and quality of collagen in the dermis were achieved with body lotion with 3HFWC (p(+)/p(-)ranged from 0.82 to 0.97). While body lotion vehiculum made collagen-water interaction more stable (p(+)/p(-)ranged from 0.3 to 0.55), hand cream with 3HFWC made it more dynamic (p(+)/p(-)ranged from 0.63 to 0.49). Body lotion vehiculum improved the compactness of the dermis (p(+)/p(-)ranged from 0.2 to 1.03), as well as commercial hand cream (p(+)/p(-) ranged from 0.28 to 0.85). Conclusion Compared to the control groups, cosmetic products with 3HFWC demonstrated positive effects on the biophysical properties of the skin. Increased paramagnetic properties are linked to more unpaired electrons, their faster movement, and, finally, better signal transduction. Thus, products with 3HFWC could enable faster regeneration of collagen and prompt skin reaction to the negative environmental influences.
PB  - Wiley, Hoboken
T2  - Journal of Cosmetic Dermatology
T1  - Influence of hyper-harmonized fullerene water complex on collagen quality and skin function
EP  - 501
IS  - 2
SP  - 494
VL  - 19
DO  - 10.1111/jocd.12999
ER  - 

@article{
author = "Miljković, Suzana and Jeftić, Branislava and Šarac, Dušan and Matović, Valentina and Slavković, Marija and Koruga, Đuro",
year = "2020",
abstract = "Background Fullerene water complex establishes the optimal order and function of biomolecules in natural, biophysical way by transducing the signal through water hydrogen bonds to biomolecules. Objectives This paper considers the effects of the patented hyper-harmonized-hydroxylated fullerene water complex (3HFWC) on biophysical properties of the skin collagen molecules. Method Optomagnetic imaging spectroscopy (OMIS) has been used for the analysis of the biophysical skin properties (diamagnetic/paramagnetic) after applying three groups of different cosmetic products. Tested cosmetic products were prepared by replacing the active ingredients with 3HFWC or with water in four commercial products. The original commercial creams and their vehiculums with water added served as control groups. Data were statistically analyzed using paired t test in R software. Results t Test gave statistically significant results for all of the products with 3HFWC, while within the control group, only body lotion and hand cream did show statistically significant results (P  lt  0.05). Significant improvements in abundance and quality of collagen in the dermis were achieved with body lotion with 3HFWC (p(+)/p(-)ranged from 0.82 to 0.97). While body lotion vehiculum made collagen-water interaction more stable (p(+)/p(-)ranged from 0.3 to 0.55), hand cream with 3HFWC made it more dynamic (p(+)/p(-)ranged from 0.63 to 0.49). Body lotion vehiculum improved the compactness of the dermis (p(+)/p(-)ranged from 0.2 to 1.03), as well as commercial hand cream (p(+)/p(-) ranged from 0.28 to 0.85). Conclusion Compared to the control groups, cosmetic products with 3HFWC demonstrated positive effects on the biophysical properties of the skin. Increased paramagnetic properties are linked to more unpaired electrons, their faster movement, and, finally, better signal transduction. Thus, products with 3HFWC could enable faster regeneration of collagen and prompt skin reaction to the negative environmental influences.",
publisher = "Wiley, Hoboken",
journal = "Journal of Cosmetic Dermatology",
title = "Influence of hyper-harmonized fullerene water complex on collagen quality and skin function",
pages = "501-494",
number = "2",
volume = "19",
doi = "10.1111/jocd.12999"
}

Miljković, S., Jeftić, B., Šarac, D., Matović, V., Slavković, M.,& Koruga, Đ.. (2020). Influence of hyper-harmonized fullerene water complex on collagen quality and skin function. in Journal of Cosmetic Dermatology
Wiley, Hoboken., 19(2), 494-501.
https://doi.org/10.1111/jocd.12999

Miljković S, Jeftić B, Šarac D, Matović V, Slavković M, Koruga Đ. Influence of hyper-harmonized fullerene water complex on collagen quality and skin function. in Journal of Cosmetic Dermatology. 2020;19(2):494-501.
doi:10.1111/jocd.12999 .

Miljković, Suzana, Jeftić, Branislava, Šarac, Dušan, Matović, Valentina, Slavković, Marija, Koruga, Đuro, "Influence of hyper-harmonized fullerene water complex on collagen quality and skin function" in Journal of Cosmetic Dermatology, 19, no. 2 (2020):494-501,
https://doi.org/10.1111/jocd.12999 . .

TY  - JOUR
AU  - Hut, Igor
AU  - Jeftić, Branislava
AU  - Matija, Lidija
AU  - Ćojbašić, Žarko
AU  - Koruga, Đuro
PY  - 2019
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3004
AB  - Semi-automated system for classification of cervical smear images based on Optomagnetic Imaging Spectroscopy (OMIS) and machine learning is proposed. Optomagnetic Imaging Spectroscopy has been applied to screen 700 cervical samples prepared according to Liquid Based Cytology (LBC) principles and to record spectra of the samples. Peak intensities and peak shift frequencies from the spectra have been used as features in classification models. Several machine learning algorithms have been tested and results of classification have been compared. Results suggest that the presented approach can be used to improve standard LBC screening tests for cervical cancer detection. Developed system enables detection of pre-cancerous and cancerous states with sensitivity of 79% and specificity of 83% along with AUC (ROC) of 88% and could be used as an improved alternative procedure for cervical cancer screening. Moreover, this can be achieved via portable apparatus and with immediately available results.
PB  - Univ Osijek, Tech Fac, Slavonski Brod
T2  - Tehnički vjesnik
T1  - Machine Learning Classification of Cervical Tissue Liquid Based Cytology Smear Images by Optomagnetic Imaging Spectroscopy
EP  - 1699
IS  - 6
SP  - 1694
VL  - 26
DO  - 10.17559/TV-20190528192618
ER  - 

@article{
author = "Hut, Igor and Jeftić, Branislava and Matija, Lidija and Ćojbašić, Žarko and Koruga, Đuro",
year = "2019",
abstract = "Semi-automated system for classification of cervical smear images based on Optomagnetic Imaging Spectroscopy (OMIS) and machine learning is proposed. Optomagnetic Imaging Spectroscopy has been applied to screen 700 cervical samples prepared according to Liquid Based Cytology (LBC) principles and to record spectra of the samples. Peak intensities and peak shift frequencies from the spectra have been used as features in classification models. Several machine learning algorithms have been tested and results of classification have been compared. Results suggest that the presented approach can be used to improve standard LBC screening tests for cervical cancer detection. Developed system enables detection of pre-cancerous and cancerous states with sensitivity of 79% and specificity of 83% along with AUC (ROC) of 88% and could be used as an improved alternative procedure for cervical cancer screening. Moreover, this can be achieved via portable apparatus and with immediately available results.",
publisher = "Univ Osijek, Tech Fac, Slavonski Brod",
journal = "Tehnički vjesnik",
title = "Machine Learning Classification of Cervical Tissue Liquid Based Cytology Smear Images by Optomagnetic Imaging Spectroscopy",
pages = "1699-1694",
number = "6",
volume = "26",
doi = "10.17559/TV-20190528192618"
}

Hut, I., Jeftić, B., Matija, L., Ćojbašić, Ž.,& Koruga, Đ.. (2019). Machine Learning Classification of Cervical Tissue Liquid Based Cytology Smear Images by Optomagnetic Imaging Spectroscopy. in Tehnički vjesnik
Univ Osijek, Tech Fac, Slavonski Brod., 26(6), 1694-1699.
https://doi.org/10.17559/TV-20190528192618

Hut I, Jeftić B, Matija L, Ćojbašić Ž, Koruga Đ. Machine Learning Classification of Cervical Tissue Liquid Based Cytology Smear Images by Optomagnetic Imaging Spectroscopy. in Tehnički vjesnik. 2019;26(6):1694-1699.
doi:10.17559/TV-20190528192618 .

Hut, Igor, Jeftić, Branislava, Matija, Lidija, Ćojbašić, Žarko, Koruga, Đuro, "Machine Learning Classification of Cervical Tissue Liquid Based Cytology Smear Images by Optomagnetic Imaging Spectroscopy" in Tehnički vjesnik, 26, no. 6 (2019):1694-1699,
https://doi.org/10.17559/TV-20190528192618 . .

TY  - JOUR
AU  - Dragičević, Aleksandra
AU  - Matija, Lidija
AU  - Krivokapić, Zoran
AU  - Dimitrijević, Ivan
AU  - Baros, Marko
AU  - Koruga, Đuro
PY  - 2019
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3106
AB  - Colorectal carcinoma (CRC) as a major health problem in industrialized countries is highly preventable and can be successfully treated in the early stages. However, incidence and mortality of CRC has increased over the last two decades. The reason could be that the current recommended options for screening are costly, unpleasant for patients, have low sensitivity and poor accessibility for screening. These reasons provide a strong rationale for the development of a new method. Opto-magnetic imaging spectroscopy (OMIS) as a new imaging method for the characterisation of various materials, including human tissues, is based on light-matter interaction, using a Poincare sphere for light properties and a Bloch sphere for electron properties, and allows the detection of biophysical characteristics within human tissue samples. Compared with histopathology examination, the OMIS method achieved an accuracy of 92.59% using Multilayer Perceptron Neural Network as a classifier, and 89.87% using Naive-Bayes, respectively. The obtained results, based on the investigation of 316 samples, both tumour and normal mucosa (162 cancer cases), strongly suggest that the new non-invasive OMIS method might be used for tissue characterization ex vivo to discriminate between the healthy and carcinoma state of the colon. However, it opens up the possibility of using the same method in in vivo studies to assist physicians in targeting biopsies of colorectal tissue.
PB  - Springer Heidelberg, Heidelberg
T2  - Journal of Medical and Biological Engineering
T1  - Classification of Healthy and Cancer States of Colon Epithelial Tissues Using Opto-magnetic Imaging Spectroscopy
EP  - 380
IS  - 3
SP  - 367
VL  - 39
DO  - 10.1007/s40846-018-0414-x
ER  - 

@article{
author = "Dragičević, Aleksandra and Matija, Lidija and Krivokapić, Zoran and Dimitrijević, Ivan and Baros, Marko and Koruga, Đuro",
year = "2019",
abstract = "Colorectal carcinoma (CRC) as a major health problem in industrialized countries is highly preventable and can be successfully treated in the early stages. However, incidence and mortality of CRC has increased over the last two decades. The reason could be that the current recommended options for screening are costly, unpleasant for patients, have low sensitivity and poor accessibility for screening. These reasons provide a strong rationale for the development of a new method. Opto-magnetic imaging spectroscopy (OMIS) as a new imaging method for the characterisation of various materials, including human tissues, is based on light-matter interaction, using a Poincare sphere for light properties and a Bloch sphere for electron properties, and allows the detection of biophysical characteristics within human tissue samples. Compared with histopathology examination, the OMIS method achieved an accuracy of 92.59% using Multilayer Perceptron Neural Network as a classifier, and 89.87% using Naive-Bayes, respectively. The obtained results, based on the investigation of 316 samples, both tumour and normal mucosa (162 cancer cases), strongly suggest that the new non-invasive OMIS method might be used for tissue characterization ex vivo to discriminate between the healthy and carcinoma state of the colon. However, it opens up the possibility of using the same method in in vivo studies to assist physicians in targeting biopsies of colorectal tissue.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Journal of Medical and Biological Engineering",
title = "Classification of Healthy and Cancer States of Colon Epithelial Tissues Using Opto-magnetic Imaging Spectroscopy",
pages = "380-367",
number = "3",
volume = "39",
doi = "10.1007/s40846-018-0414-x"
}

Dragičević, A., Matija, L., Krivokapić, Z., Dimitrijević, I., Baros, M.,& Koruga, Đ.. (2019). Classification of Healthy and Cancer States of Colon Epithelial Tissues Using Opto-magnetic Imaging Spectroscopy. in Journal of Medical and Biological Engineering
Springer Heidelberg, Heidelberg., 39(3), 367-380.
https://doi.org/10.1007/s40846-018-0414-x

Dragičević A, Matija L, Krivokapić Z, Dimitrijević I, Baros M, Koruga Đ. Classification of Healthy and Cancer States of Colon Epithelial Tissues Using Opto-magnetic Imaging Spectroscopy. in Journal of Medical and Biological Engineering. 2019;39(3):367-380.
doi:10.1007/s40846-018-0414-x .

Dragičević, Aleksandra, Matija, Lidija, Krivokapić, Zoran, Dimitrijević, Ivan, Baros, Marko, Koruga, Đuro, "Classification of Healthy and Cancer States of Colon Epithelial Tissues Using Opto-magnetic Imaging Spectroscopy" in Journal of Medical and Biological Engineering, 39, no. 3 (2019):367-380,
https://doi.org/10.1007/s40846-018-0414-x . .

TY  - CHAP
AU  - Jovanović, Tamara
AU  - Koruga, Đuro
AU  - Jovančićević, Branimir
PY  - 2019
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/5338
AB  - The stable isomers of the higher fullerenes C76 and C84 with D2 symmetry as well as the basic fullerenes C60 and C70 were isolated from carbon soot and characterized by the new and advanced methods, techniques, and processes. The validity of several semiempirical, ab initio, and DFT theoretical calculations in predicting the general pattern of IR absorption and the vibrational frequencies, as well as the molecular electronic structure of the C76 and C84 isomers of D2 symmetry, is confirmed, based on recent experimental results. An excellent correlation was found between the previously reported theoretical data and the recently obtained experimental results for these molecules over the relevant spectral range for the identification of fullerenes. These results indicate that there are no errors in the calculations in the significant spectral regions, the assumptions that were based on previous comparisons with partial experimental results Isolated fullerenes are important for their applications in electronic and optical devices, solar cells, optical limiting, sensors, polymers, nanophotonic materials, diagnostic and therapeutic agents, health and environment protection, and so forth.
T2  - Top 5 Contributions in Nanotechnology: 4th Edition
T1  - Chapter Recent Advances in IR and UV/VIS Spectroscopic Characterization of the C76 and C84 Isomers of D2 Symmetry
UR  - https://hdl.handle.net/21.15107/rcub_machinery_5338
ER  - 

@inbook{
author = "Jovanović, Tamara and Koruga, Đuro and Jovančićević, Branimir",
year = "2019",
abstract = "The stable isomers of the higher fullerenes C76 and C84 with D2 symmetry as well as the basic fullerenes C60 and C70 were isolated from carbon soot and characterized by the new and advanced methods, techniques, and processes. The validity of several semiempirical, ab initio, and DFT theoretical calculations in predicting the general pattern of IR absorption and the vibrational frequencies, as well as the molecular electronic structure of the C76 and C84 isomers of D2 symmetry, is confirmed, based on recent experimental results. An excellent correlation was found between the previously reported theoretical data and the recently obtained experimental results for these molecules over the relevant spectral range for the identification of fullerenes. These results indicate that there are no errors in the calculations in the significant spectral regions, the assumptions that were based on previous comparisons with partial experimental results Isolated fullerenes are important for their applications in electronic and optical devices, solar cells, optical limiting, sensors, polymers, nanophotonic materials, diagnostic and therapeutic agents, health and environment protection, and so forth.",
journal = "Top 5 Contributions in Nanotechnology: 4th Edition",
booktitle = "Chapter Recent Advances in IR and UV/VIS Spectroscopic Characterization of the C76 and C84 Isomers of D2 Symmetry",
url = "https://hdl.handle.net/21.15107/rcub_machinery_5338"
}

Jovanović, T., Koruga, Đ.,& Jovančićević, B.. (2019). Chapter Recent Advances in IR and UV/VIS Spectroscopic Characterization of the C76 and C84 Isomers of D2 Symmetry. in Top 5 Contributions in Nanotechnology: 4th Edition.
https://hdl.handle.net/21.15107/rcub_machinery_5338

Jovanović T, Koruga Đ, Jovančićević B. Chapter Recent Advances in IR and UV/VIS Spectroscopic Characterization of the C76 and C84 Isomers of D2 Symmetry. in Top 5 Contributions in Nanotechnology: 4th Edition. 2019;.
https://hdl.handle.net/21.15107/rcub_machinery_5338 .

Jovanović, Tamara, Koruga, Đuro, Jovančićević, Branimir, "Chapter Recent Advances in IR and UV/VIS Spectroscopic Characterization of the C76 and C84 Isomers of D2 Symmetry" in Top 5 Contributions in Nanotechnology: 4th Edition (2019),
https://hdl.handle.net/21.15107/rcub_machinery_5338 .

TY  - CONF
AU  - Kojić, Dušan
AU  - Matija, Lidija
AU  - Petrov, Ljubiša
AU  - Koruga, Đuro
PY  - 2019
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3188
PB  - Czech Technical University
C3  - Proceedings - 25th Danubia-Adria Symposium on Advances in Experimental Mechanics, DAS 2008
T1  - Mechanical properties of human skin studied by atomic force microscope
EP  - 122
SP  - 121
UR  - https://hdl.handle.net/21.15107/rcub_machinery_3188
ER  - 

@conference{
author = "Kojić, Dušan and Matija, Lidija and Petrov, Ljubiša and Koruga, Đuro",
year = "2019",
publisher = "Czech Technical University",
journal = "Proceedings - 25th Danubia-Adria Symposium on Advances in Experimental Mechanics, DAS 2008",
title = "Mechanical properties of human skin studied by atomic force microscope",
pages = "122-121",
url = "https://hdl.handle.net/21.15107/rcub_machinery_3188"
}

Kojić, D., Matija, L., Petrov, L.,& Koruga, Đ.. (2019). Mechanical properties of human skin studied by atomic force microscope. in Proceedings - 25th Danubia-Adria Symposium on Advances in Experimental Mechanics, DAS 2008
Czech Technical University., 121-122.
https://hdl.handle.net/21.15107/rcub_machinery_3188

Kojić D, Matija L, Petrov L, Koruga Đ. Mechanical properties of human skin studied by atomic force microscope. in Proceedings - 25th Danubia-Adria Symposium on Advances in Experimental Mechanics, DAS 2008. 2019;:121-122.
https://hdl.handle.net/21.15107/rcub_machinery_3188 .

Kojić, Dušan, Matija, Lidija, Petrov, Ljubiša, Koruga, Đuro, "Mechanical properties of human skin studied by atomic force microscope" in Proceedings - 25th Danubia-Adria Symposium on Advances in Experimental Mechanics, DAS 2008 (2019):121-122,
https://hdl.handle.net/21.15107/rcub_machinery_3188 .

TY  - CONF
AU  - Matija, Lidija
AU  - Kojić, Dušan
AU  - Petrov, Ljubiša
AU  - Koruga, Đuro
PY  - 2019
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3198
PB  - Czech Technical University
C3  - Proceedings - 25th Danubia-Adria Symposium on Advances in Experimental Mechanics, DAS 2008
T1  - Mechanical properties of surfaces studied by atomic force microscope
EP  - 170
SP  - 169
UR  - https://hdl.handle.net/21.15107/rcub_machinery_3198
ER  - 

@conference{
author = "Matija, Lidija and Kojić, Dušan and Petrov, Ljubiša and Koruga, Đuro",
year = "2019",
publisher = "Czech Technical University",
journal = "Proceedings - 25th Danubia-Adria Symposium on Advances in Experimental Mechanics, DAS 2008",
title = "Mechanical properties of surfaces studied by atomic force microscope",
pages = "170-169",
url = "https://hdl.handle.net/21.15107/rcub_machinery_3198"
}

Matija, L., Kojić, D., Petrov, L.,& Koruga, Đ.. (2019). Mechanical properties of surfaces studied by atomic force microscope. in Proceedings - 25th Danubia-Adria Symposium on Advances in Experimental Mechanics, DAS 2008
Czech Technical University., 169-170.
https://hdl.handle.net/21.15107/rcub_machinery_3198

Matija L, Kojić D, Petrov L, Koruga Đ. Mechanical properties of surfaces studied by atomic force microscope. in Proceedings - 25th Danubia-Adria Symposium on Advances in Experimental Mechanics, DAS 2008. 2019;:169-170.
https://hdl.handle.net/21.15107/rcub_machinery_3198 .

Matija, Lidija, Kojić, Dušan, Petrov, Ljubiša, Koruga, Đuro, "Mechanical properties of surfaces studied by atomic force microscope" in Proceedings - 25th Danubia-Adria Symposium on Advances in Experimental Mechanics, DAS 2008 (2019):169-170,
https://hdl.handle.net/21.15107/rcub_machinery_3198 .

TY  - JOUR
AU  - Jeftić, Branislava
AU  - Matija, Lidija
AU  - Koruga, Đuro
PY  - 2019
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3154
AB  - Optomagnetna imidžing spektroskopija pokazala je visok procenat tačnosti u klasifikaciji bioloških tkiva, posebno kada se radi o uzorcima grlića materice, usne duplje i debelog creva. Ova metoda omogućava detekciju abnormalnog tkiva i ćelija i stoga može da se koristi kao dijagnostički test u okviru skrining programa. U prethodnim studijama analizirani su cervikalni uzorci i uzorci dobijeni tehnikom citologije na tečnoj bazi pomoću optomagnetne imidžing spektroskopije u cilju detekcije karcinoma grlića materice i pokazano je da ova metoda može da razdvoji zdravo tkivo od kancera. Do sada su testirani samo binarni klasifikacioni modeli za kasifikaciju cervikalnih uzoraka na bazi optomagnetnih spektara uzoraka. U ovom radu testirana je klasifikacija Papanikolaou razmaza u četiri klase (II, III, IV i V Papanikolaou grupe) korišćenjem klasifikacionog modela na bazi Random Forest klasifikatora koji je pokazao interklasnu senzitivnost od 49,25%, 58,97%, 50%, 44,44% za II, III, IV i V Papanikolau grupu respektivno, i specifičnost od 65,26%, 54,76%, 98,70% i 98,69% za II, III, IV i V Papanikolau grupu respektivno.
AB  - Optomagnetic Imaging Spectroscopy demonstrated high percentages of accuracy in biological sample classification, namely cervical, oral and colon samples. It enables detection of abnormal tissue and cells, and thus can be used as a diagnostic tool in screening programs. Papanicolaou smears and liquid based cytology samples were analysed in previous studies on cervical cancer detection by Optomagnetic Imaging Spectroscopy and it was shown that this method can diferentiate normal healthy tissue from the cancer tissue. So far, only binary classification of the cervical samples was performed based on optomagnetic spectra of the samples. In this paper, classification of the Papanicolaou smears into four groups (II, III, IV and V Papanicolaou groups) was tested with the Random Forest classification model that demonstrated interclass sensitivity of 49.25%, 58.97%, 50%, 44.44% for II, III, IV and V Papanicolaou group respectively, and specificity of 65.26%, 54.76%, 98.70% and 98.69% for II, III, IV and V Papanicolaou group respectively.
T2  - Contemporary materials
T1  - Novi pristup otkrivanja abnormalnih ćelija grlića materice
T1  - New approach to detection of abnormal cervical cells
EP  - 136
IS  - 2
SP  - 132
VL  - 10
DO  - 10.7251/COMEN1902132J
ER  - 

@article{
author = "Jeftić, Branislava and Matija, Lidija and Koruga, Đuro",
year = "2019",
abstract = "Optomagnetna imidžing spektroskopija pokazala je visok procenat tačnosti u klasifikaciji bioloških tkiva, posebno kada se radi o uzorcima grlića materice, usne duplje i debelog creva. Ova metoda omogućava detekciju abnormalnog tkiva i ćelija i stoga može da se koristi kao dijagnostički test u okviru skrining programa. U prethodnim studijama analizirani su cervikalni uzorci i uzorci dobijeni tehnikom citologije na tečnoj bazi pomoću optomagnetne imidžing spektroskopije u cilju detekcije karcinoma grlića materice i pokazano je da ova metoda može da razdvoji zdravo tkivo od kancera. Do sada su testirani samo binarni klasifikacioni modeli za kasifikaciju cervikalnih uzoraka na bazi optomagnetnih spektara uzoraka. U ovom radu testirana je klasifikacija Papanikolaou razmaza u četiri klase (II, III, IV i V Papanikolaou grupe) korišćenjem klasifikacionog modela na bazi Random Forest klasifikatora koji je pokazao interklasnu senzitivnost od 49,25%, 58,97%, 50%, 44,44% za II, III, IV i V Papanikolau grupu respektivno, i specifičnost od 65,26%, 54,76%, 98,70% i 98,69% za II, III, IV i V Papanikolau grupu respektivno., Optomagnetic Imaging Spectroscopy demonstrated high percentages of accuracy in biological sample classification, namely cervical, oral and colon samples. It enables detection of abnormal tissue and cells, and thus can be used as a diagnostic tool in screening programs. Papanicolaou smears and liquid based cytology samples were analysed in previous studies on cervical cancer detection by Optomagnetic Imaging Spectroscopy and it was shown that this method can diferentiate normal healthy tissue from the cancer tissue. So far, only binary classification of the cervical samples was performed based on optomagnetic spectra of the samples. In this paper, classification of the Papanicolaou smears into four groups (II, III, IV and V Papanicolaou groups) was tested with the Random Forest classification model that demonstrated interclass sensitivity of 49.25%, 58.97%, 50%, 44.44% for II, III, IV and V Papanicolaou group respectively, and specificity of 65.26%, 54.76%, 98.70% and 98.69% for II, III, IV and V Papanicolaou group respectively.",
journal = "Contemporary materials",
title = "Novi pristup otkrivanja abnormalnih ćelija grlića materice, New approach to detection of abnormal cervical cells",
pages = "136-132",
number = "2",
volume = "10",
doi = "10.7251/COMEN1902132J"
}

Jeftić, B., Matija, L.,& Koruga, Đ.. (2019). Novi pristup otkrivanja abnormalnih ćelija grlića materice. in Contemporary materials, 10(2), 132-136.
https://doi.org/10.7251/COMEN1902132J

Jeftić B, Matija L, Koruga Đ. Novi pristup otkrivanja abnormalnih ćelija grlića materice. in Contemporary materials. 2019;10(2):132-136.
doi:10.7251/COMEN1902132J .

Jeftić, Branislava, Matija, Lidija, Koruga, Đuro, "Novi pristup otkrivanja abnormalnih ćelija grlića materice" in Contemporary materials, 10, no. 2 (2019):132-136,
https://doi.org/10.7251/COMEN1902132J . .

TY  - CHAP
AU  - Matija, Lidija
AU  - Munćan, Jelena S.
AU  - Mileusnić, Ivana
AU  - Koruga, Đuro
PY  - 2017
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/2698
AB  - In this chapter the investigation of a new type of nanomaterial, nanoharmonized substance (NHS) whose composition of matter follows a harmonized form (Fibonacci law: Φ/ϕ) is presented. Conducting its vibrations to water molecules in near surroundings could force biomolecules to recover its natural vibration mode.The discovery of fullerene material brought new possibilities in science and technology. However, it is toxic in concentrations higher than 10 ppb. To overcome this problem, a water stabilizing belt has been made around carbon hydroxyl molecule and in the range of 106-109 ppb it becomes nontoxic. Energetically stabilized nanoharmonized substance could be considered biomimetic nanomaterial, which mostly in its symmetrical and energetically properties resembles clathrin-a protein with the most important process of intracellular transportation. To investigate properties and efficiency of nanoharmonized substance (NHS), Aquaphotomics is used alongside gold standard biopsy and tissue examination.
PB  - Elsevier
T2  - Nano- and Microscale Drug Delivery Systems: Design and Fabrication
T1  - Fibonacci Nanostructures for Novel Nanotherapeutical Approach
EP  - 74
SP  - 49
DO  - 10.1016/B978-0-323-52727-9.00004-2
ER  - 

@inbook{
author = "Matija, Lidija and Munćan, Jelena S. and Mileusnić, Ivana and Koruga, Đuro",
year = "2017",
abstract = "In this chapter the investigation of a new type of nanomaterial, nanoharmonized substance (NHS) whose composition of matter follows a harmonized form (Fibonacci law: Φ/ϕ) is presented. Conducting its vibrations to water molecules in near surroundings could force biomolecules to recover its natural vibration mode.The discovery of fullerene material brought new possibilities in science and technology. However, it is toxic in concentrations higher than 10 ppb. To overcome this problem, a water stabilizing belt has been made around carbon hydroxyl molecule and in the range of 106-109 ppb it becomes nontoxic. Energetically stabilized nanoharmonized substance could be considered biomimetic nanomaterial, which mostly in its symmetrical and energetically properties resembles clathrin-a protein with the most important process of intracellular transportation. To investigate properties and efficiency of nanoharmonized substance (NHS), Aquaphotomics is used alongside gold standard biopsy and tissue examination.",
publisher = "Elsevier",
journal = "Nano- and Microscale Drug Delivery Systems: Design and Fabrication",
booktitle = "Fibonacci Nanostructures for Novel Nanotherapeutical Approach",
pages = "74-49",
doi = "10.1016/B978-0-323-52727-9.00004-2"
}

Matija, L., Munćan, J. S., Mileusnić, I.,& Koruga, Đ.. (2017). Fibonacci Nanostructures for Novel Nanotherapeutical Approach. in Nano- and Microscale Drug Delivery Systems: Design and Fabrication
Elsevier., 49-74.
https://doi.org/10.1016/B978-0-323-52727-9.00004-2

Matija L, Munćan JS, Mileusnić I, Koruga Đ. Fibonacci Nanostructures for Novel Nanotherapeutical Approach. in Nano- and Microscale Drug Delivery Systems: Design and Fabrication. 2017;:49-74.
doi:10.1016/B978-0-323-52727-9.00004-2 .

Matija, Lidija, Munćan, Jelena S., Mileusnić, Ivana, Koruga, Đuro, "Fibonacci Nanostructures for Novel Nanotherapeutical Approach" in Nano- and Microscale Drug Delivery Systems: Design and Fabrication (2017):49-74,
https://doi.org/10.1016/B978-0-323-52727-9.00004-2 . .

TY  - JOUR
AU  - Tomić, Marija
AU  - Bojović, Božica
AU  - Stamenković, Dragomir
AU  - Mileusnić, Ivana
AU  - Koruga, Đuro
PY  - 2017
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/2613
AB  - The aim was to develop new materials that would, after appropriate machining processes, improve the surface roughness and wettability of contact lenses. The samples used in this investigation were standard rigid gas-permeable (RGP) SOLEKO contact lenses, made of poly-MMA-co-siloxy silane methacrylate material (known under the commercial name SP40 (TM)), and its modifications by adding three nanomaterials: fullerene C-60 (designated as SP40-A), fullerol C-60(OH)(24) (designated as SP40-B) and methformin hydroxylate fullerene C-60(OH)(12)(OC4N5H10)(12) (designated as SP40-C). Both atomic force microscopy (AFM) and magnetic force microscopy (MFM) were used to measure the topography and gradient of the magnetic field of the nanophotonic materials and the reference samples. According to the magnetic properties of all the materials yielded by MFM it can be concluded that adding fullerene and its derivatives certainly reduces the spectrum of the phase shifts angle by almost 50 %, which increases the paramagnetic characteristics of the nanophotonic material. The positive result of nanophotonic materials characterization is the fact that the roughness parameter values for all of these materials, are lower than those for the basic material. A surface lacunarity analysis, based on in-house procedures for determining the lacunarity value of contact lens surfaces, confirms the influence of surface topology on the tear film volume distribution and, consequently, the contact lens' surface lubrication. The presence of carbon nanomaterials, according to the surface roughness parameters, are improved for rigid gas-permeable (RGP) contact lenses made from nanophotonic polymer materials compared to those produced from the basic material.
PB  - Inst Za Kovinske Materiale I In Tehnologie, Ljubjana
T2  - Materiali in Tehnologije
T1  - Lacunarity properties of nanophotonic materials based on poly(methyl methacrylate) for contact lenses
EP  - 151
IS  - 1
SP  - 145
VL  - 51
DO  - 10.17222/mit.2016.014
ER  - 

@article{
author = "Tomić, Marija and Bojović, Božica and Stamenković, Dragomir and Mileusnić, Ivana and Koruga, Đuro",
year = "2017",
abstract = "The aim was to develop new materials that would, after appropriate machining processes, improve the surface roughness and wettability of contact lenses. The samples used in this investigation were standard rigid gas-permeable (RGP) SOLEKO contact lenses, made of poly-MMA-co-siloxy silane methacrylate material (known under the commercial name SP40 (TM)), and its modifications by adding three nanomaterials: fullerene C-60 (designated as SP40-A), fullerol C-60(OH)(24) (designated as SP40-B) and methformin hydroxylate fullerene C-60(OH)(12)(OC4N5H10)(12) (designated as SP40-C). Both atomic force microscopy (AFM) and magnetic force microscopy (MFM) were used to measure the topography and gradient of the magnetic field of the nanophotonic materials and the reference samples. According to the magnetic properties of all the materials yielded by MFM it can be concluded that adding fullerene and its derivatives certainly reduces the spectrum of the phase shifts angle by almost 50 %, which increases the paramagnetic characteristics of the nanophotonic material. The positive result of nanophotonic materials characterization is the fact that the roughness parameter values for all of these materials, are lower than those for the basic material. A surface lacunarity analysis, based on in-house procedures for determining the lacunarity value of contact lens surfaces, confirms the influence of surface topology on the tear film volume distribution and, consequently, the contact lens' surface lubrication. The presence of carbon nanomaterials, according to the surface roughness parameters, are improved for rigid gas-permeable (RGP) contact lenses made from nanophotonic polymer materials compared to those produced from the basic material.",
publisher = "Inst Za Kovinske Materiale I In Tehnologie, Ljubjana",
journal = "Materiali in Tehnologije",
title = "Lacunarity properties of nanophotonic materials based on poly(methyl methacrylate) for contact lenses",
pages = "151-145",
number = "1",
volume = "51",
doi = "10.17222/mit.2016.014"
}

Tomić, M., Bojović, B., Stamenković, D., Mileusnić, I.,& Koruga, Đ.. (2017). Lacunarity properties of nanophotonic materials based on poly(methyl methacrylate) for contact lenses. in Materiali in Tehnologije
Inst Za Kovinske Materiale I In Tehnologie, Ljubjana., 51(1), 145-151.
https://doi.org/10.17222/mit.2016.014

Tomić M, Bojović B, Stamenković D, Mileusnić I, Koruga Đ. Lacunarity properties of nanophotonic materials based on poly(methyl methacrylate) for contact lenses. in Materiali in Tehnologije. 2017;51(1):145-151.
doi:10.17222/mit.2016.014 .

Tomić, Marija, Bojović, Božica, Stamenković, Dragomir, Mileusnić, Ivana, Koruga, Đuro, "Lacunarity properties of nanophotonic materials based on poly(methyl methacrylate) for contact lenses" in Materiali in Tehnologije, 51, no. 1 (2017):145-151,
https://doi.org/10.17222/mit.2016.014 . .

TY  - CONF
AU  - Jovanović, Tamara
AU  - Koruga, Đuro
AU  - Jovančićević, Branimir
PY  - 2017
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/5484
AB  - The higher fullerenes C76-D2 and C84-D2:22, as well as the basic fullerenes C60 and C70 were
chromatographically isolated from carbon soot and the fullerol C60(OH)24 was synthesized, using new and advanced methods and processes. Their FT-IR(KBr) and electronic absorption spectra were recorded. All the observed infrared and UV/VIS bands are in excellent agreement with the theoretical calculations for these molecules. The molar absorptivity, as well as the integrated molar absorptivity of the absorption bands of the obtained fullerene nanomaterials was
determined. These results are significant for their identification and quantitative determination
either in natural resources or in artificially synthesized materials, electronic and optical devices,
polymers, sensors, diagnostic and therapeutic agents, solar cells, nanophotonic lenses with optical absorption properties closer to human eye light sensitivity that can be used for early diagnosis of diabetes, in applied optical science, biomedical engineering and industry etc.
C3  - The Nineteenth Annual Conference Yucomat 2017 Programme and The Book of Abstracts, Herceg Novi, September 4-8,
T1  - Comparative spectroscopic characterization of fullerene nanomaterials
SP  - 107
UR  - https://hdl.handle.net/21.15107/rcub_machinery_5484
ER  - 

@conference{
author = "Jovanović, Tamara and Koruga, Đuro and Jovančićević, Branimir",
year = "2017",
abstract = "The higher fullerenes C76-D2 and C84-D2:22, as well as the basic fullerenes C60 and C70 were
chromatographically isolated from carbon soot and the fullerol C60(OH)24 was synthesized, using new and advanced methods and processes. Their FT-IR(KBr) and electronic absorption spectra were recorded. All the observed infrared and UV/VIS bands are in excellent agreement with the theoretical calculations for these molecules. The molar absorptivity, as well as the integrated molar absorptivity of the absorption bands of the obtained fullerene nanomaterials was
determined. These results are significant for their identification and quantitative determination
either in natural resources or in artificially synthesized materials, electronic and optical devices,
polymers, sensors, diagnostic and therapeutic agents, solar cells, nanophotonic lenses with optical absorption properties closer to human eye light sensitivity that can be used for early diagnosis of diabetes, in applied optical science, biomedical engineering and industry etc.",
journal = "The Nineteenth Annual Conference Yucomat 2017 Programme and The Book of Abstracts, Herceg Novi, September 4-8,",
title = "Comparative spectroscopic characterization of fullerene nanomaterials",
pages = "107",
url = "https://hdl.handle.net/21.15107/rcub_machinery_5484"
}

Jovanović, T., Koruga, Đ.,& Jovančićević, B.. (2017). Comparative spectroscopic characterization of fullerene nanomaterials. in The Nineteenth Annual Conference Yucomat 2017 Programme and The Book of Abstracts, Herceg Novi, September 4-8,, 107.
https://hdl.handle.net/21.15107/rcub_machinery_5484

Jovanović T, Koruga Đ, Jovančićević B. Comparative spectroscopic characterization of fullerene nanomaterials. in The Nineteenth Annual Conference Yucomat 2017 Programme and The Book of Abstracts, Herceg Novi, September 4-8,. 2017;:107.
https://hdl.handle.net/21.15107/rcub_machinery_5484 .

Jovanović, Tamara, Koruga, Đuro, Jovančićević, Branimir, "Comparative spectroscopic characterization of fullerene nanomaterials" in The Nineteenth Annual Conference Yucomat 2017 Programme and The Book of Abstracts, Herceg Novi, September 4-8, (2017):107,
https://hdl.handle.net/21.15107/rcub_machinery_5484 .

TY  - JOUR
AU  - Jovanović, Tamara
AU  - Koruga, Đuro
AU  - Jovančićević, Branimir
PY  - 2017
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/5181
AB  - The FT-IR spectra of the stable C76 and C84 isomers ofD2 symmetry, isolated by the new, advanced extraction and chromatographic methods and processes, were recorded by the KBr technique, over the relevant region from400 to 2000 cm−1, at room temperature. All the observed infrared bands are in excellent agreement with the semiempirical QCFF/PI, DFT, and TB potential calculations for these fullerenes, which is presented in this article, as the evidence of their validity. The molar absorptivity 𝜀��� and the integrated molar absorptivity 𝜓��� of their IR absorption bands were determined and reported together with the relative intensities. Excellent
agreement is found between the relative intensities of the main and characteristic absorption maxima calculated from 𝜀��� 𝜆��� and from the 𝜓��� 𝜆��� values in adequate integration ranges. These results are significant for the identification and quantitative determination of the C76-D2 and C84-D2:22 fullerenes, either in natural resources on Earth and in space or in artificially synthesized and biomaterials, electronic, optical, and biomedical devices, sensors, polymers, optical limiters, solar cells, organic field effect transistors, special lenses, diagnostic and therapeutic agents, pharmaceutical substances in biomedical engineering, and so forth.
T2  - Journal of Nanomaterials
T1  - The IR Spectra, Molar Absorptivity, and Integrated Molar Absorptivity of the C76-D2 and C84-D2:22 Isomers
SP  - 4360746
DO  - 10.1155/2017/4360746
ER  - 

@article{
author = "Jovanović, Tamara and Koruga, Đuro and Jovančićević, Branimir",
year = "2017",
abstract = "The FT-IR spectra of the stable C76 and C84 isomers ofD2 symmetry, isolated by the new, advanced extraction and chromatographic methods and processes, were recorded by the KBr technique, over the relevant region from400 to 2000 cm−1, at room temperature. All the observed infrared bands are in excellent agreement with the semiempirical QCFF/PI, DFT, and TB potential calculations for these fullerenes, which is presented in this article, as the evidence of their validity. The molar absorptivity 𝜀��� and the integrated molar absorptivity 𝜓��� of their IR absorption bands were determined and reported together with the relative intensities. Excellent
agreement is found between the relative intensities of the main and characteristic absorption maxima calculated from 𝜀��� 𝜆��� and from the 𝜓��� 𝜆��� values in adequate integration ranges. These results are significant for the identification and quantitative determination of the C76-D2 and C84-D2:22 fullerenes, either in natural resources on Earth and in space or in artificially synthesized and biomaterials, electronic, optical, and biomedical devices, sensors, polymers, optical limiters, solar cells, organic field effect transistors, special lenses, diagnostic and therapeutic agents, pharmaceutical substances in biomedical engineering, and so forth.",
journal = "Journal of Nanomaterials",
title = "The IR Spectra, Molar Absorptivity, and Integrated Molar Absorptivity of the C76-D2 and C84-D2:22 Isomers",
pages = "4360746",
doi = "10.1155/2017/4360746"
}

Jovanović, T., Koruga, Đ.,& Jovančićević, B.. (2017). The IR Spectra, Molar Absorptivity, and Integrated Molar Absorptivity of the C76-D2 and C84-D2:22 Isomers. in Journal of Nanomaterials, 4360746.
https://doi.org/10.1155/2017/4360746

Jovanović T, Koruga Đ, Jovančićević B. The IR Spectra, Molar Absorptivity, and Integrated Molar Absorptivity of the C76-D2 and C84-D2:22 Isomers. in Journal of Nanomaterials. 2017;:4360746.
doi:10.1155/2017/4360746 .

Jovanović, Tamara, Koruga, Đuro, Jovančićević, Branimir, "The IR Spectra, Molar Absorptivity, and Integrated Molar Absorptivity of the C76-D2 and C84-D2:22 Isomers" in Journal of Nanomaterials (2017):4360746,
https://doi.org/10.1155/2017/4360746 . .

TY  - JOUR
AU  - Jeftić, Branislava
AU  - Papić-Obradović, Milena
AU  - Munćan, Jelena S.
AU  - Matija, Lidija
AU  - Koruga, Đuro
PY  - 2017
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/2561
AB  - Cervical cancer is the fourth most common cancer worldwide. The fact that cervical cancer takes many years to develop indicates that mortality rates can be significantly decreased with early detection. This is why screening tests for early cervical cancer detection are so important, especially in developing countries where screening programs are not available to the same extent as in developed countries. About 84% of all cervical cancer cases in 2012 occurred in less developed countries mainly due to the lack of effective screening programs. Even if the necessary infrastructure in one country exists, the cost of screening test is usually too high. Finally, the accuracy of screening test needs to be satisfying in order to detect all the abnormal cases and treat them effectively. Papanicolaou test is still the most effective screening test for cervical cancer detection so far. However, the accuracy of Papanicolaou test is closely related to the expertise of the cytopathologist and therefore the accuracy varies producing relatively low sensitivity of Papanicolaou test (50-85%). HPV DNA test is approved as primary screening test, but so far it gives better results when it is used in conjunction with cytology. We present a method and device for detection of cervical cancer based on optomagnetic imaging spectroscopy (OMIS) and compare the results for cancer detection using stained and fresh unstained cervical cell samples. Compared to stained samples, unstained fresh sample classification by OMIS into healthy/cancerous group with Na  lt  ve Bayes classifier gave higher accuracy (96% compared to 85,18%).
PB  - Springer Heidelberg, Heidelberg
T2  - Journal of Medical and Biological Engineering
T1  - Optomagnetic Imaging Spectroscopy Application in Cervical Dysplasia and Cancer Detection: Comparation of Stained and Unstained Papanicolaou Smears
EP  - 943
IS  - 6
SP  - 936
VL  - 37
DO  - 10.1007/s40846-017-0255-z
ER  - 

@article{
author = "Jeftić, Branislava and Papić-Obradović, Milena and Munćan, Jelena S. and Matija, Lidija and Koruga, Đuro",
year = "2017",
abstract = "Cervical cancer is the fourth most common cancer worldwide. The fact that cervical cancer takes many years to develop indicates that mortality rates can be significantly decreased with early detection. This is why screening tests for early cervical cancer detection are so important, especially in developing countries where screening programs are not available to the same extent as in developed countries. About 84% of all cervical cancer cases in 2012 occurred in less developed countries mainly due to the lack of effective screening programs. Even if the necessary infrastructure in one country exists, the cost of screening test is usually too high. Finally, the accuracy of screening test needs to be satisfying in order to detect all the abnormal cases and treat them effectively. Papanicolaou test is still the most effective screening test for cervical cancer detection so far. However, the accuracy of Papanicolaou test is closely related to the expertise of the cytopathologist and therefore the accuracy varies producing relatively low sensitivity of Papanicolaou test (50-85%). HPV DNA test is approved as primary screening test, but so far it gives better results when it is used in conjunction with cytology. We present a method and device for detection of cervical cancer based on optomagnetic imaging spectroscopy (OMIS) and compare the results for cancer detection using stained and fresh unstained cervical cell samples. Compared to stained samples, unstained fresh sample classification by OMIS into healthy/cancerous group with Na  lt  ve Bayes classifier gave higher accuracy (96% compared to 85,18%).",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Journal of Medical and Biological Engineering",
title = "Optomagnetic Imaging Spectroscopy Application in Cervical Dysplasia and Cancer Detection: Comparation of Stained and Unstained Papanicolaou Smears",
pages = "943-936",
number = "6",
volume = "37",
doi = "10.1007/s40846-017-0255-z"
}

Jeftić, B., Papić-Obradović, M., Munćan, J. S., Matija, L.,& Koruga, Đ.. (2017). Optomagnetic Imaging Spectroscopy Application in Cervical Dysplasia and Cancer Detection: Comparation of Stained and Unstained Papanicolaou Smears. in Journal of Medical and Biological Engineering
Springer Heidelberg, Heidelberg., 37(6), 936-943.
https://doi.org/10.1007/s40846-017-0255-z

Jeftić B, Papić-Obradović M, Munćan JS, Matija L, Koruga Đ. Optomagnetic Imaging Spectroscopy Application in Cervical Dysplasia and Cancer Detection: Comparation of Stained and Unstained Papanicolaou Smears. in Journal of Medical and Biological Engineering. 2017;37(6):936-943.
doi:10.1007/s40846-017-0255-z .

Jeftić, Branislava, Papić-Obradović, Milena, Munćan, Jelena S., Matija, Lidija, Koruga, Đuro, "Optomagnetic Imaging Spectroscopy Application in Cervical Dysplasia and Cancer Detection: Comparation of Stained and Unstained Papanicolaou Smears" in Journal of Medical and Biological Engineering, 37, no. 6 (2017):936-943,
https://doi.org/10.1007/s40846-017-0255-z . .

TY  - JOUR
AU  - Tomić, Marija
AU  - Vasić-Milovanović, Aleksandra
AU  - Matija, Lidija
AU  - Koruga, Đuro
PY  - 2016
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/2333
AB  - The problem of low solubility of fullerene is surpassed by its functionalization with -OH groups making a new molecule called fullerol C-60(OH)(24). Materials used in this study are synthesized by incorporating fullerol into commercial soft contact lens material Definitive74 made by Contamac, UK. Three different mass concentrations of fullerol are used: 0.003%, 0.01% and 0.015%. Hence, three materials are produced and the fourth material, the standard one, was used as a reference sample. The purpose of incorporating fullerol into polymer was to develop new materials for soft contact lenses with improved optical and mechanical characteristics. The magnetic properties of polymers change due to fullerol presence therefore the aim was to show the differences in magnetic properties of the materials before and after the exposure to four different external influences. The measurements of a remanent magnetization of these materials are done by spinner magnetometer, JR-6A.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Fullerenes Nanotubes and Carbon Nanostructures
T1  - Remanent magnetization measurements of polymeric materials containing fullerol C-60(OH)(24) before and after exposure to external magnetic field
EP  - 426
IS  - 7
SP  - 423
VL  - 24
DO  - 10.1080/1536383X.2016.1172571
ER  - 

@article{
author = "Tomić, Marija and Vasić-Milovanović, Aleksandra and Matija, Lidija and Koruga, Đuro",
year = "2016",
abstract = "The problem of low solubility of fullerene is surpassed by its functionalization with -OH groups making a new molecule called fullerol C-60(OH)(24). Materials used in this study are synthesized by incorporating fullerol into commercial soft contact lens material Definitive74 made by Contamac, UK. Three different mass concentrations of fullerol are used: 0.003%, 0.01% and 0.015%. Hence, three materials are produced and the fourth material, the standard one, was used as a reference sample. The purpose of incorporating fullerol into polymer was to develop new materials for soft contact lenses with improved optical and mechanical characteristics. The magnetic properties of polymers change due to fullerol presence therefore the aim was to show the differences in magnetic properties of the materials before and after the exposure to four different external influences. The measurements of a remanent magnetization of these materials are done by spinner magnetometer, JR-6A.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Fullerenes Nanotubes and Carbon Nanostructures",
title = "Remanent magnetization measurements of polymeric materials containing fullerol C-60(OH)(24) before and after exposure to external magnetic field",
pages = "426-423",
number = "7",
volume = "24",
doi = "10.1080/1536383X.2016.1172571"
}

Tomić, M., Vasić-Milovanović, A., Matija, L.,& Koruga, Đ.. (2016). Remanent magnetization measurements of polymeric materials containing fullerol C-60(OH)(24) before and after exposure to external magnetic field. in Fullerenes Nanotubes and Carbon Nanostructures
Taylor & Francis Inc, Philadelphia., 24(7), 423-426.
https://doi.org/10.1080/1536383X.2016.1172571

Tomić M, Vasić-Milovanović A, Matija L, Koruga Đ. Remanent magnetization measurements of polymeric materials containing fullerol C-60(OH)(24) before and after exposure to external magnetic field. in Fullerenes Nanotubes and Carbon Nanostructures. 2016;24(7):423-426.
doi:10.1080/1536383X.2016.1172571 .

Tomić, Marija, Vasić-Milovanović, Aleksandra, Matija, Lidija, Koruga, Đuro, "Remanent magnetization measurements of polymeric materials containing fullerol C-60(OH)(24) before and after exposure to external magnetic field" in Fullerenes Nanotubes and Carbon Nanostructures, 24, no. 7 (2016):423-426,
https://doi.org/10.1080/1536383X.2016.1172571 . .

TY  - JOUR
AU  - Papić-Obradović, Milena
AU  - Jeftić, Branislava
AU  - Dragičević, Aleksandra
AU  - Munćan, Jelena S.
AU  - Matija, Lidija
AU  - Koruga, Đuro
PY  - 2015
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/2250
PB  - Elsevier Sci Ltd, Oxford
T2  - European Journal of Cancer
T1  - Optomagnetic imaging spectroscopy in characterisation of cervical tissue and cancer detection using unstained sample approach
EP  - S130
SP  - S130
VL  - 51
DO  - 10.1016/S0959-8049(16)30380-X
ER  - 

@article{
author = "Papić-Obradović, Milena and Jeftić, Branislava and Dragičević, Aleksandra and Munćan, Jelena S. and Matija, Lidija and Koruga, Đuro",
year = "2015",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "European Journal of Cancer",
title = "Optomagnetic imaging spectroscopy in characterisation of cervical tissue and cancer detection using unstained sample approach",
pages = "S130-S130",
volume = "51",
doi = "10.1016/S0959-8049(16)30380-X"
}

Papić-Obradović, M., Jeftić, B., Dragičević, A., Munćan, J. S., Matija, L.,& Koruga, Đ.. (2015). Optomagnetic imaging spectroscopy in characterisation of cervical tissue and cancer detection using unstained sample approach. in European Journal of Cancer
Elsevier Sci Ltd, Oxford., 51, S130-S130.
https://doi.org/10.1016/S0959-8049(16)30380-X

Papić-Obradović M, Jeftić B, Dragičević A, Munćan JS, Matija L, Koruga Đ. Optomagnetic imaging spectroscopy in characterisation of cervical tissue and cancer detection using unstained sample approach. in European Journal of Cancer. 2015;51:S130-S130.
doi:10.1016/S0959-8049(16)30380-X .

Papić-Obradović, Milena, Jeftić, Branislava, Dragičević, Aleksandra, Munćan, Jelena S., Matija, Lidija, Koruga, Đuro, "Optomagnetic imaging spectroscopy in characterisation of cervical tissue and cancer detection using unstained sample approach" in European Journal of Cancer, 51 (2015):S130-S130,
https://doi.org/10.1016/S0959-8049(16)30380-X . .

TY  - GEN
AU  - Papić-Obradović, Milena
AU  - Đukić, Milan
AU  - Jeftić, Branislava
AU  - Dragičević, Aleksandra
AU  - Matija, Lidija
AU  - Koruga, Đuro
PY  - 2015
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/5849
AB  - Карцином грлића материце у нашој земљи је други водећи узрок оболевања и четврти узрок умирања међу женском популацијом са преко 1300 новооболелих и приближно 500 умрлих случајева. Инциденца ендометријалног карцинома на територији Србије је 17,9 новооболелих на 100,000 жена. Нaнoтeхнoлoгиja je дo сaдa унапредила мнoгe нaучнe oблaсти. Тeхнoлoгиja ради нa скaли грaдивних eлeмeнaтa људскe ћeлиje, имa пoтeнциjaл рaзвoja урeђaja кojи су мaњи и eфикaсниjи oд свих дo сaдa пoстojeћих. Знaчaj примeнe нaнoтeхнoлoгиja у мeдицини oглeдa сe у пoтeнциjaлу дa дoпринeсe рaзвojу нoвих диjaгнoстичких мeтoдa и рaнoм oткривaњу бoлeсти, кao и пoбoљшaнoм тeрaпиjскoм учинку кoришћeњeм систeмa зa циљaнo дeлoвaњe и кoнтрoлисaнo oтпуштaњe лeкoвитих
супстaнци. Као резултат дугогодишњег истраживања и рада на развоју нова оптичке методе за нанодијагностиковање карцинома засноване на нанотехнологијама, настала је oптoмaгнeтнa имиџинг спeктрoскoпиja (OMИС), која се показала валидном за карактеризацију ПАП размаза и рану детекцију карцинома грлића материце, као и за карактеризацију узорака ендометријалног карцинома. Метода Оптомагнетне спектроскопије је јефтинија и брза и њеним увођењем у клиничку праксу и комбиновањем са постојећим методама могао би се побољшати тренутни проценат тачно постављених дијагноза. С обзиром да је аутоматизована, метода искључује
субјективни фактор, а самим тим смањује могућност појављивања грешке при постављању дијагнозе.
PB  - Društvo doktora medicine Republike Srpske
T2  - Društvo doktora medicine Republike Srpske
T1  - Nanotehnološke osnove Optomagnetne spektroskopije i njena primena u ginekologiji: karakterizacija tkiva grlića materice i endometrijuma
UR  - https://hdl.handle.net/21.15107/rcub_machinery_5849
ER  - 

@misc{
author = "Papić-Obradović, Milena and Đukić, Milan and Jeftić, Branislava and Dragičević, Aleksandra and Matija, Lidija and Koruga, Đuro",
year = "2015",
abstract = "Карцином грлића материце у нашој земљи је други водећи узрок оболевања и четврти узрок умирања међу женском популацијом са преко 1300 новооболелих и приближно 500 умрлих случајева. Инциденца ендометријалног карцинома на територији Србије је 17,9 новооболелих на 100,000 жена. Нaнoтeхнoлoгиja je дo сaдa унапредила мнoгe нaучнe oблaсти. Тeхнoлoгиja ради нa скaли грaдивних eлeмeнaтa људскe ћeлиje, имa пoтeнциjaл рaзвoja урeђaja кojи су мaњи и eфикaсниjи oд свих дo сaдa пoстojeћих. Знaчaj примeнe нaнoтeхнoлoгиja у мeдицини oглeдa сe у пoтeнциjaлу дa дoпринeсe рaзвojу нoвих диjaгнoстичких мeтoдa и рaнoм oткривaњу бoлeсти, кao и пoбoљшaнoм тeрaпиjскoм учинку кoришћeњeм систeмa зa циљaнo дeлoвaњe и кoнтрoлисaнo oтпуштaњe лeкoвитих
супстaнци. Као резултат дугогодишњег истраживања и рада на развоју нова оптичке методе за нанодијагностиковање карцинома засноване на нанотехнологијама, настала је oптoмaгнeтнa имиџинг спeктрoскoпиja (OMИС), која се показала валидном за карактеризацију ПАП размаза и рану детекцију карцинома грлића материце, као и за карактеризацију узорака ендометријалног карцинома. Метода Оптомагнетне спектроскопије је јефтинија и брза и њеним увођењем у клиничку праксу и комбиновањем са постојећим методама могао би се побољшати тренутни проценат тачно постављених дијагноза. С обзиром да је аутоматизована, метода искључује
субјективни фактор, а самим тим смањује могућност појављивања грешке при постављању дијагнозе.",
publisher = "Društvo doktora medicine Republike Srpske",
journal = "Društvo doktora medicine Republike Srpske",
title = "Nanotehnološke osnove Optomagnetne spektroskopije i njena primena u ginekologiji: karakterizacija tkiva grlića materice i endometrijuma",
url = "https://hdl.handle.net/21.15107/rcub_machinery_5849"
}

Papić-Obradović, M., Đukić, M., Jeftić, B., Dragičević, A., Matija, L.,& Koruga, Đ.. (2015). Nanotehnološke osnove Optomagnetne spektroskopije i njena primena u ginekologiji: karakterizacija tkiva grlića materice i endometrijuma. in Društvo doktora medicine Republike Srpske
Društvo doktora medicine Republike Srpske..
https://hdl.handle.net/21.15107/rcub_machinery_5849

Papić-Obradović M, Đukić M, Jeftić B, Dragičević A, Matija L, Koruga Đ. Nanotehnološke osnove Optomagnetne spektroskopije i njena primena u ginekologiji: karakterizacija tkiva grlića materice i endometrijuma. in Društvo doktora medicine Republike Srpske. 2015;.
https://hdl.handle.net/21.15107/rcub_machinery_5849 .

Papić-Obradović, Milena, Đukić, Milan, Jeftić, Branislava, Dragičević, Aleksandra, Matija, Lidija, Koruga, Đuro, "Nanotehnološke osnove Optomagnetne spektroskopije i njena primena u ginekologiji: karakterizacija tkiva grlića materice i endometrijuma" in Društvo doktora medicine Republike Srpske (2015),
https://hdl.handle.net/21.15107/rcub_machinery_5849 .

TY  - JOUR
AU  - Sedlar, Mariana
AU  - Nikolić, Gorana
AU  - Dragičević, Aleksandra
AU  - Koruga, Đuro
PY  - 2015
UR  - https://www.doiserbia.nb.rs/Article.aspx?id=0042-84501500077S#.ZA0JgHZKhEZ
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/5846
AB  - Background/aim: Opto-magnetic imaging spectroscopy (OMIS) was used as a novel method to detemine tissue molecular conformation changes during hyperbaric oxygen (HBO) therapy. The aim of this study was to examine the usefulness of OMIS for the assessment of HBO therapy effectiveness on the diseased tissue.

Methods: OMIS is concerned with obtaining paramagnetic/diamagnetic properties of materials, related to the presence of unpaired/paired electrons based on their interaction with visible light. The basic tool is light of wavelength in the range between 400 nm and 700 nm and its interaction with tissue. The study included 22 subjects: 16 angiopathy patients and 6 healthy subjects as the control group. OMIS was used with patients on the 1st, 10th and 20th session and with the control group on the 1st, 10th and 20th day without HBO therapy in between.

Results: The obtained results showed that healthy skin of all the control group subjects had the same shape curve. In the angiopathy patient group, before the first session OMIS showed tissue disorder and after the last session results resembled more closely the results in healthy tissue. The differences in the tissue state in the angiopathy group before each session were noticeable, showing normalized tissue under the influence of HBO.

Conclusion: The results show that OMIS could be used as a diagnostic tool for detection of the tissue state before and after the HBO therapy.
PB  - Serbian Army
T2  - Vojnosanitetski pregled
T1  - Opto-magnetic imaging spectroscopy in characterization of the tissues during hyperbaric oxygen therapy
EP  - 927
SP  - 922
VL  - 72
DO  - 10.2298/vsp140610077s
ER  - 

@article{
author = "Sedlar, Mariana and Nikolić, Gorana and Dragičević, Aleksandra and Koruga, Đuro",
year = "2015",
abstract = "Background/aim: Opto-magnetic imaging spectroscopy (OMIS) was used as a novel method to detemine tissue molecular conformation changes during hyperbaric oxygen (HBO) therapy. The aim of this study was to examine the usefulness of OMIS for the assessment of HBO therapy effectiveness on the diseased tissue.

Methods: OMIS is concerned with obtaining paramagnetic/diamagnetic properties of materials, related to the presence of unpaired/paired electrons based on their interaction with visible light. The basic tool is light of wavelength in the range between 400 nm and 700 nm and its interaction with tissue. The study included 22 subjects: 16 angiopathy patients and 6 healthy subjects as the control group. OMIS was used with patients on the 1st, 10th and 20th session and with the control group on the 1st, 10th and 20th day without HBO therapy in between.

Results: The obtained results showed that healthy skin of all the control group subjects had the same shape curve. In the angiopathy patient group, before the first session OMIS showed tissue disorder and after the last session results resembled more closely the results in healthy tissue. The differences in the tissue state in the angiopathy group before each session were noticeable, showing normalized tissue under the influence of HBO.

Conclusion: The results show that OMIS could be used as a diagnostic tool for detection of the tissue state before and after the HBO therapy.",
publisher = "Serbian Army",
journal = "Vojnosanitetski pregled",
title = "Opto-magnetic imaging spectroscopy in characterization of the tissues during hyperbaric oxygen therapy",
pages = "927-922",
volume = "72",
doi = "10.2298/vsp140610077s"
}

Sedlar, M., Nikolić, G., Dragičević, A.,& Koruga, Đ.. (2015). Opto-magnetic imaging spectroscopy in characterization of the tissues during hyperbaric oxygen therapy. in Vojnosanitetski pregled
Serbian Army., 72, 922-927.
https://doi.org/10.2298/vsp140610077s

Sedlar M, Nikolić G, Dragičević A, Koruga Đ. Opto-magnetic imaging spectroscopy in characterization of the tissues during hyperbaric oxygen therapy. in Vojnosanitetski pregled. 2015;72:922-927.
doi:10.2298/vsp140610077s .

Sedlar, Mariana, Nikolić, Gorana, Dragičević, Aleksandra, Koruga, Đuro, "Opto-magnetic imaging spectroscopy in characterization of the tissues during hyperbaric oxygen therapy" in Vojnosanitetski pregled, 72 (2015):922-927,
https://doi.org/10.2298/vsp140610077s . .