TY  - JOUR
AU  - Rudolf, Rebeka
AU  - Jelen, Z.
AU  - Zadravec, M.
AU  - Majerić, P.
AU  - Jović, Zorana
AU  - Vuksanović, M.
AU  - Stanković, Ivana
AU  - Matija, Lidija
AU  - Dragičević, Aleksandra
AU  - Thompson, Miso N.
AU  - Horvat, A.
AU  - Koruga, Đuro
PY  - 2022
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3772
AB  - Three types of gold nanoparticles (AuNPs) were synthesised with a custom-made Ultrasonic Spray Pyrolysis (USP) device, from aqueous solutions of gold (III) chloride (AuCl3) and gold (III) acetate (AuC6H12O6), with an initial concentration of Au 0.5 g/L. AuNPs were collected in suspensions of deionised (D.I.) water with the stabilisers polyvinylpyrrolidone (PVP) or polyethylene glycol (PEG), followed by the process of freeze drying the AuNPs to be useful as a new additive for the cream. The standard cream base was used as a matrix for preparation of three types of cream with AuNPs in the same concentration ratios. The third AuNPs cream was prepared with a patented hydroxylated fullerene water complex (3HFWC-W) matrix. To examine the effect of AuNPs as additive in creams, a six-week study of test creams was conducted on 33 volunteers with no dermatological diseases. During the study three main parameters of the skin where measured: Collagen quality, skin moisturisation and the epidermis-dermis function. The results of the study found improvements of collagen quality between 18-24 %, achieved due to the use of AuNPs in standard creams, while the cream with the combination of 3HFWC-W and AuNPs gave significantly higher improvements with a value of 45.7 %. It was also discovered that hydration of the skin (stratum cornum) increased by 6.4-9.6 % in standard creams with AuNPs, and 73.7 % in the 3HFWC/AuNPs' cream. Similar results were measured by the epidermisdermis function, where 24-28 % improvement for standard creams with AuNPs was identified, and 38.4 % for the cream 3HFWC-W/AuNPs.
PB  - Univ Maribor, Fac Mechanical Engineering, Maribor
T2  - Advances in Production Engineering & Management
T1  - A gold nanoparticles and hydroxylated fullerene water complex as a new product for cosmetics
EP  - 107
IS  - 1
SP  - 89
VL  - 17
DO  - 10.14743/apem2022.1.423
ER  - 

@article{
author = "Rudolf, Rebeka and Jelen, Z. and Zadravec, M. and Majerić, P. and Jović, Zorana and Vuksanović, M. and Stanković, Ivana and Matija, Lidija and Dragičević, Aleksandra and Thompson, Miso N. and Horvat, A. and Koruga, Đuro",
year = "2022",
abstract = "Three types of gold nanoparticles (AuNPs) were synthesised with a custom-made Ultrasonic Spray Pyrolysis (USP) device, from aqueous solutions of gold (III) chloride (AuCl3) and gold (III) acetate (AuC6H12O6), with an initial concentration of Au 0.5 g/L. AuNPs were collected in suspensions of deionised (D.I.) water with the stabilisers polyvinylpyrrolidone (PVP) or polyethylene glycol (PEG), followed by the process of freeze drying the AuNPs to be useful as a new additive for the cream. The standard cream base was used as a matrix for preparation of three types of cream with AuNPs in the same concentration ratios. The third AuNPs cream was prepared with a patented hydroxylated fullerene water complex (3HFWC-W) matrix. To examine the effect of AuNPs as additive in creams, a six-week study of test creams was conducted on 33 volunteers with no dermatological diseases. During the study three main parameters of the skin where measured: Collagen quality, skin moisturisation and the epidermis-dermis function. The results of the study found improvements of collagen quality between 18-24 %, achieved due to the use of AuNPs in standard creams, while the cream with the combination of 3HFWC-W and AuNPs gave significantly higher improvements with a value of 45.7 %. It was also discovered that hydration of the skin (stratum cornum) increased by 6.4-9.6 % in standard creams with AuNPs, and 73.7 % in the 3HFWC/AuNPs' cream. Similar results were measured by the epidermisdermis function, where 24-28 % improvement for standard creams with AuNPs was identified, and 38.4 % for the cream 3HFWC-W/AuNPs.",
publisher = "Univ Maribor, Fac Mechanical Engineering, Maribor",
journal = "Advances in Production Engineering & Management",
title = "A gold nanoparticles and hydroxylated fullerene water complex as a new product for cosmetics",
pages = "107-89",
number = "1",
volume = "17",
doi = "10.14743/apem2022.1.423"
}

Rudolf, R., Jelen, Z., Zadravec, M., Majerić, P., Jović, Z., Vuksanović, M., Stanković, I., Matija, L., Dragičević, A., Thompson, M. N., Horvat, A.,& Koruga, Đ.. (2022). A gold nanoparticles and hydroxylated fullerene water complex as a new product for cosmetics. in Advances in Production Engineering & Management
Univ Maribor, Fac Mechanical Engineering, Maribor., 17(1), 89-107.
https://doi.org/10.14743/apem2022.1.423

Rudolf R, Jelen Z, Zadravec M, Majerić P, Jović Z, Vuksanović M, Stanković I, Matija L, Dragičević A, Thompson MN, Horvat A, Koruga Đ. A gold nanoparticles and hydroxylated fullerene water complex as a new product for cosmetics. in Advances in Production Engineering & Management. 2022;17(1):89-107.
doi:10.14743/apem2022.1.423 .

Rudolf, Rebeka, Jelen, Z., Zadravec, M., Majerić, P., Jović, Zorana, Vuksanović, M., Stanković, Ivana, Matija, Lidija, Dragičević, Aleksandra, Thompson, Miso N., Horvat, A., Koruga, Đuro, "A gold nanoparticles and hydroxylated fullerene water complex as a new product for cosmetics" in Advances in Production Engineering & Management, 17, no. 1 (2022):89-107,
https://doi.org/10.14743/apem2022.1.423 . .

TY  - CONF
AU  - Draca, Dijana
AU  - Markelić, Milica
AU  - Mojić, Marija
AU  - Jelaca, Sanja
AU  - Mijatović, Sanja
AU  - Jović, Zorana
AU  - Dragičević, Aleksandra
AU  - Koruga, Đuro
AU  - Maksimović-Ivanić, Danijela
PY  - 2021
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3488
PB  - Wiley, Hoboken
C3  - European Journal of Immunology
T1  - Anti-melanoma effects of Hyper-harmonized hydroxylated fullerene water complex and hyperpolarized light in vivo
EP  - 353
SP  - 353
VL  - 51
UR  - https://hdl.handle.net/21.15107/rcub_machinery_3488
ER  - 

@conference{
author = "Draca, Dijana and Markelić, Milica and Mojić, Marija and Jelaca, Sanja and Mijatović, Sanja and Jović, Zorana and Dragičević, Aleksandra and Koruga, Đuro and Maksimović-Ivanić, Danijela",
year = "2021",
publisher = "Wiley, Hoboken",
journal = "European Journal of Immunology",
title = "Anti-melanoma effects of Hyper-harmonized hydroxylated fullerene water complex and hyperpolarized light in vivo",
pages = "353-353",
volume = "51",
url = "https://hdl.handle.net/21.15107/rcub_machinery_3488"
}

Draca, D., Markelić, M., Mojić, M., Jelaca, S., Mijatović, S., Jović, Z., Dragičević, A., Koruga, Đ.,& Maksimović-Ivanić, D.. (2021). Anti-melanoma effects of Hyper-harmonized hydroxylated fullerene water complex and hyperpolarized light in vivo. in European Journal of Immunology
Wiley, Hoboken., 51, 353-353.
https://hdl.handle.net/21.15107/rcub_machinery_3488

Draca D, Markelić M, Mojić M, Jelaca S, Mijatović S, Jović Z, Dragičević A, Koruga Đ, Maksimović-Ivanić D. Anti-melanoma effects of Hyper-harmonized hydroxylated fullerene water complex and hyperpolarized light in vivo. in European Journal of Immunology. 2021;51:353-353.
https://hdl.handle.net/21.15107/rcub_machinery_3488 .

Draca, Dijana, Markelić, Milica, Mojić, Marija, Jelaca, Sanja, Mijatović, Sanja, Jović, Zorana, Dragičević, Aleksandra, Koruga, Đuro, Maksimović-Ivanić, Danijela, "Anti-melanoma effects of Hyper-harmonized hydroxylated fullerene water complex and hyperpolarized light in vivo" in European Journal of Immunology, 51 (2021):353-353,
https://hdl.handle.net/21.15107/rcub_machinery_3488 .

TY  - JOUR
AU  - Lazović, Jelena
AU  - Zopf, Lydia M.
AU  - Hren, Jernej
AU  - Gajdos, Martin
AU  - Slavković, Marija
AU  - Jović, Zorana
AU  - Stanković, Ivana
AU  - Matović, Valentina
AU  - Koruga, Đuro
PY  - 2021
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/3541
AB  - The most symmetric molecule, Buckminster fullerene C-60, due to its unique properties, has been intensively studied for various medical and technological advances. Minimally invasive and minimally toxic treatments hold great promise for future applications. With this in mind, this research exploited the physical properties of fullerene molecules for potential therapeutic effects. Pristine fullerenes have peak absorbance in the 380-500 nm range, making them an attractive violet-blue light filter. Since spectral quality of light can affect behavior, this research used resting state functional magnetic resonance imaging (rs fMRI) and behavioral testing to directly evaluate the effects of fullerene-filtered light on brain processing and behavior in mice. The same method was used to study if hydroxyl fullerene water complexes (3HFWC), with or without fullerene-filtered light, modulated brain processing. A month-long, daily exposure to fullerene-filtered light led to decreased activation of the brain area involved in emotional processing (amygdala). Water supplemented with 3HFWC resulted in an activation of brain areas involved in pain modulation and processing (periaqueductal gray), and decreased latency to first reaction when tested with a hot plate. The combination of fullerene-filtered light with 3HFWC in drinking water led to restored sensitivity to a hot plate and activation of brain areas involved in cognitive functions (prelimbic, anterior cingulate and retrosplenial cortex). These results uncovered the potential of fullerene-filtered light to impact emotional processing and modulate pain perception, indicating its further use in stress and pain management.
PB  - MDPI, Basel
T2  - Symmetry
T1  - Fullerene-Filtered Light Spectrum and Fullerenes Modulate Emotional and Pain Processing in Mice
IS  - 11
VL  - 13
DO  - 10.3390/sym13112004
ER  - 

@article{
author = "Lazović, Jelena and Zopf, Lydia M. and Hren, Jernej and Gajdos, Martin and Slavković, Marija and Jović, Zorana and Stanković, Ivana and Matović, Valentina and Koruga, Đuro",
year = "2021",
abstract = "The most symmetric molecule, Buckminster fullerene C-60, due to its unique properties, has been intensively studied for various medical and technological advances. Minimally invasive and minimally toxic treatments hold great promise for future applications. With this in mind, this research exploited the physical properties of fullerene molecules for potential therapeutic effects. Pristine fullerenes have peak absorbance in the 380-500 nm range, making them an attractive violet-blue light filter. Since spectral quality of light can affect behavior, this research used resting state functional magnetic resonance imaging (rs fMRI) and behavioral testing to directly evaluate the effects of fullerene-filtered light on brain processing and behavior in mice. The same method was used to study if hydroxyl fullerene water complexes (3HFWC), with or without fullerene-filtered light, modulated brain processing. A month-long, daily exposure to fullerene-filtered light led to decreased activation of the brain area involved in emotional processing (amygdala). Water supplemented with 3HFWC resulted in an activation of brain areas involved in pain modulation and processing (periaqueductal gray), and decreased latency to first reaction when tested with a hot plate. The combination of fullerene-filtered light with 3HFWC in drinking water led to restored sensitivity to a hot plate and activation of brain areas involved in cognitive functions (prelimbic, anterior cingulate and retrosplenial cortex). These results uncovered the potential of fullerene-filtered light to impact emotional processing and modulate pain perception, indicating its further use in stress and pain management.",
publisher = "MDPI, Basel",
journal = "Symmetry",
title = "Fullerene-Filtered Light Spectrum and Fullerenes Modulate Emotional and Pain Processing in Mice",
number = "11",
volume = "13",
doi = "10.3390/sym13112004"
}

Lazović, J., Zopf, L. M., Hren, J., Gajdos, M., Slavković, M., Jović, Z., Stanković, I., Matović, V.,& Koruga, Đ.. (2021). Fullerene-Filtered Light Spectrum and Fullerenes Modulate Emotional and Pain Processing in Mice. in Symmetry
MDPI, Basel., 13(11).
https://doi.org/10.3390/sym13112004

Lazović J, Zopf LM, Hren J, Gajdos M, Slavković M, Jović Z, Stanković I, Matović V, Koruga Đ. Fullerene-Filtered Light Spectrum and Fullerenes Modulate Emotional and Pain Processing in Mice. in Symmetry. 2021;13(11).
doi:10.3390/sym13112004 .

Lazović, Jelena, Zopf, Lydia M., Hren, Jernej, Gajdos, Martin, Slavković, Marija, Jović, Zorana, Stanković, Ivana, Matović, Valentina, Koruga, Đuro, "Fullerene-Filtered Light Spectrum and Fullerenes Modulate Emotional and Pain Processing in Mice" in Symmetry, 13, no. 11 (2021),
https://doi.org/10.3390/sym13112004 . .