dc.creator | Hedrih, Andjelka | |
dc.creator | Lazarević, Mihailo | |
dc.creator | Mitrović-Jovanović, Ana | |
dc.date.accessioned | 2023-03-23T09:55:35Z | |
dc.date.available | 2023-03-23T09:55:35Z | |
dc.date.issued | 2013 | |
dc.identifier.isbn | 978-86-917073-0-9 | |
dc.identifier.uri | https://machinery.mas.bg.ac.rs/handle/123456789/6612 | |
dc.description.abstract | The quality of a whole ejaculate is important for fertilization success. Number of
sperm with effective swimming velocity, capable to reach the oocyte and to undergo
complex adaptations within the female reproductive tract is a key determinant of male
fertilization success. According to the literature, total sperm numbers are positively
correlated to proportions of normal sperm, acrosome integrity and motile sperm and
also with gonadosomatic index.
Treating the fertilization process as an oscillatory phenomenon we use oscillatory
spherical net model of mouse Zona Pellucida (mZP) to investigate the impact of
sperm count on successful fertilization. To describe impact of number of
hyperactivated sperm cells relative to the oscillatory behaviour of mZP, the discreet
continuum model in the form of spherical net model is used. mZP is modelled as a
discrete system of material particles (corresponds to mZP glycoproteins)
interconnected with massless linear elastic elements on a manner that preserves molar
ratio of m ZP glycoproteins. According to the model, under external numerous vibroimpacts
of spermatozoa, mZP oscillatory net oscillates in forced regimes.
To estimate the influence of sperm count a numerical analysis was conducted. Using
generalized Lissajous curves, parametric frequency analysis of oscillatory behaviour
of ZP1 molecules in oscillatory model of mZP is realized. Numerical analysis
identified favourable oscillatory states of ZP1 molecules under the impact of different
number of spermatozoa with effective velocity.
We can conclude that ZP1 molecules in the mZP oscillatory model have different
oscillatory states when exposed to the external vibro -impacts of different number of
hyperactivated spermatozoa, indicated that certain number of hyperactivated
spermatozoa is necessary for reaching the favourable oscillatory state of mZP for
fertilisation. | sr |
dc.language.iso | en | sr |
dc.publisher | Beograd : Udruženje za reproduktivno zdravlje | sr |
dc.rights | closedAccess | sr |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.source | Abstract book the 7th diczfalusy award lecture symposium on reproductive health 27 - 28. septembar 2013, Belgrade | sr |
dc.subject | sperm kinetic parameters | sr |
dc.subject | sperm count | sr |
dc.subject | Zona pellucida | sr |
dc.subject | oscillations | sr |
dc.subject | discreet continuum model | sr |
dc.subject | Lissajous curves | sr |
dc.title | Importance of number of hyperactivated spermatozoa for successful fertilisation trough mechanical oscillatory model of mouse zona pellucida | sr |
dc.type | conferenceObject | sr |
dc.rights.license | BY | sr |
dc.citation.epage | 2 | |
dc.citation.rank | M34 | |
dc.citation.spage | 1 | |
dc.description.other | COBISS.SR-ID 200977932 | sr |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_machinery_6612 | |
dc.type.version | publishedVersion | sr |