TY  - JOUR
AU  - Matić, Tamara
AU  - Ležaja Zebić, Maja
AU  - Miletić, Vesna
AU  - Trajković, Isaak
AU  - Milošević, Miloš
AU  - Račić, Aleksandar
AU  - Veljović, Djordje
PY  - 2023
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/7573
AB  - This study aimed to (1) comparatively analyze properties of Sr- and Mg-substituted hydroxyapatite (HAP)-based dental inserts; (2) evaluate insert bonding to restorative materials, and (3) evaluate the effect of doped HAP inserts on fracture resistance (FR) of human molars with large occlusal restorations. By ion-doping with Sr or Mg, 3 insert types were obtained and characterized using XRD, SEM, Vickers hardness and fracture toughness. Shear bond strength (SBS) was determined between acid etched or unetched inserts and following materials: Maxcem cement (Kerr); Filtek Z250 (3M) bonded with Single Bond Universal (SBU; 3M) or Clearfil Universal (Cf; Kuraray). Modified Class I cavities were prepared in 16 intact molars and restored using insert + composite or composite only (control) (n = 8/group). FR of restored molars was determined by static load until fracture upon thermal cycling. Fracture toughness was similar between Sr/Mg-doped inserts (0.94–1.04 MPam−1/2 p = .429). Mg-doped inserts showed greater hardness (range 4.78–5.15 GPa) than Sr6 inserts (3.74 ± 0.31 GPa; p < .05). SBS for SBU and Cf adhesives (range 7.19–15.93 MPa) was higher than for Maxcem (range 3.07–5.95 MPa) (p < .05). There was no significant difference in FR between molars restored with insert-containing and control restorations (3.00 ± 0.30 kN and 3.22 ± 0.42 kN, respectively; p > .05). HAP-based inserts doped with Mg/Sr had different composition and mechanical properties. Adhesive bonding to inserts resulted in greater bond strength than cementation, which may be improved by insert acid-etching. Ion-doped HAP inserts did not affect FR of restored molars. In conclusion, HAP-based dental inserts may potentially replace dentin in large cavities, without affecting fracture resistance of restored teeth.
PB  - Wiley
T2  - Jurnal of biomedical materials research Part B: Applied Biomaterials
T1  - Hydroxyapatite-based dental inserts: Microstructure, mechanical properties, bonding efficiency and fracture resistance of molars with occlusal restorations
IS  - 1
VL  - 112
DO  - 10.1002/jbm.b.35331
ER  - 

@article{
author = "Matić, Tamara and Ležaja Zebić, Maja and Miletić, Vesna and Trajković, Isaak and Milošević, Miloš and Račić, Aleksandar and Veljović, Djordje",
year = "2023",
abstract = "This study aimed to (1) comparatively analyze properties of Sr- and Mg-substituted hydroxyapatite (HAP)-based dental inserts; (2) evaluate insert bonding to restorative materials, and (3) evaluate the effect of doped HAP inserts on fracture resistance (FR) of human molars with large occlusal restorations. By ion-doping with Sr or Mg, 3 insert types were obtained and characterized using XRD, SEM, Vickers hardness and fracture toughness. Shear bond strength (SBS) was determined between acid etched or unetched inserts and following materials: Maxcem cement (Kerr); Filtek Z250 (3M) bonded with Single Bond Universal (SBU; 3M) or Clearfil Universal (Cf; Kuraray). Modified Class I cavities were prepared in 16 intact molars and restored using insert + composite or composite only (control) (n = 8/group). FR of restored molars was determined by static load until fracture upon thermal cycling. Fracture toughness was similar between Sr/Mg-doped inserts (0.94–1.04 MPam−1/2 p = .429). Mg-doped inserts showed greater hardness (range 4.78–5.15 GPa) than Sr6 inserts (3.74 ± 0.31 GPa; p < .05). SBS for SBU and Cf adhesives (range 7.19–15.93 MPa) was higher than for Maxcem (range 3.07–5.95 MPa) (p < .05). There was no significant difference in FR between molars restored with insert-containing and control restorations (3.00 ± 0.30 kN and 3.22 ± 0.42 kN, respectively; p > .05). HAP-based inserts doped with Mg/Sr had different composition and mechanical properties. Adhesive bonding to inserts resulted in greater bond strength than cementation, which may be improved by insert acid-etching. Ion-doped HAP inserts did not affect FR of restored molars. In conclusion, HAP-based dental inserts may potentially replace dentin in large cavities, without affecting fracture resistance of restored teeth.",
publisher = "Wiley",
journal = "Jurnal of biomedical materials research Part B: Applied Biomaterials",
title = "Hydroxyapatite-based dental inserts: Microstructure, mechanical properties, bonding efficiency and fracture resistance of molars with occlusal restorations",
number = "1",
volume = "112",
doi = "10.1002/jbm.b.35331"
}

Matić, T., Ležaja Zebić, M., Miletić, V., Trajković, I., Milošević, M., Račić, A.,& Veljović, D.. (2023). Hydroxyapatite-based dental inserts: Microstructure, mechanical properties, bonding efficiency and fracture resistance of molars with occlusal restorations. in Jurnal of biomedical materials research Part B: Applied Biomaterials
Wiley., 112(1).
https://doi.org/10.1002/jbm.b.35331

Matić T, Ležaja Zebić M, Miletić V, Trajković I, Milošević M, Račić A, Veljović D. Hydroxyapatite-based dental inserts: Microstructure, mechanical properties, bonding efficiency and fracture resistance of molars with occlusal restorations. in Jurnal of biomedical materials research Part B: Applied Biomaterials. 2023;112(1).
doi:10.1002/jbm.b.35331 .

Matić, Tamara, Ležaja Zebić, Maja, Miletić, Vesna, Trajković, Isaak, Milošević, Miloš, Račić, Aleksandar, Veljović, Djordje, "Hydroxyapatite-based dental inserts: Microstructure, mechanical properties, bonding efficiency and fracture resistance of molars with occlusal restorations" in Jurnal of biomedical materials research Part B: Applied Biomaterials, 112, no. 1 (2023),
https://doi.org/10.1002/jbm.b.35331 . .