TY  - JOUR
AU  - Hedrih, Andjelka
AU  - Lazarević, Mihailo
AU  - Mitrović-Jovanović, Ana
PY  - 2015
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/2238
AB  - According to the available literature, penetrating sperm creates an oblique path trough Zona pellucida (ZP) - the most outer surface of oocytes. Considering fertilization process as an oscillatory phenomenon, the influence of sperm impact angle relative to the oscillatory behavior of mouse ZP is described by using the discrete continuum mechanical model in the form of a spherical net model. A parametric frequency analysis of oscillatory behavior of knot material particles in the mouse ZP (mZP) spherical net model is conducted by using generalized Lussajous curves. The influence of impact angles of sperm cells on the corresponding knot mass particles' resultant trajectory is discussed. Favorable sperm impact angles for successful fertilization are identified.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Computers in Biology and Medicine
T1  - Influence of sperm impact angle on successful fertilization through mZP oscillatory spherical net model
EP  - 29
SP  - 19
VL  - 59
DO  - 10.1016/j.compbiomed.2015.01.009
ER  - 

@article{
author = "Hedrih, Andjelka and Lazarević, Mihailo and Mitrović-Jovanović, Ana",
year = "2015",
abstract = "According to the available literature, penetrating sperm creates an oblique path trough Zona pellucida (ZP) - the most outer surface of oocytes. Considering fertilization process as an oscillatory phenomenon, the influence of sperm impact angle relative to the oscillatory behavior of mouse ZP is described by using the discrete continuum mechanical model in the form of a spherical net model. A parametric frequency analysis of oscillatory behavior of knot material particles in the mouse ZP (mZP) spherical net model is conducted by using generalized Lussajous curves. The influence of impact angles of sperm cells on the corresponding knot mass particles' resultant trajectory is discussed. Favorable sperm impact angles for successful fertilization are identified.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Computers in Biology and Medicine",
title = "Influence of sperm impact angle on successful fertilization through mZP oscillatory spherical net model",
pages = "29-19",
volume = "59",
doi = "10.1016/j.compbiomed.2015.01.009"
}

Hedrih, A., Lazarević, M.,& Mitrović-Jovanović, A.. (2015). Influence of sperm impact angle on successful fertilization through mZP oscillatory spherical net model. in Computers in Biology and Medicine
Pergamon-Elsevier Science Ltd, Oxford., 59, 19-29.
https://doi.org/10.1016/j.compbiomed.2015.01.009

Hedrih A, Lazarević M, Mitrović-Jovanović A. Influence of sperm impact angle on successful fertilization through mZP oscillatory spherical net model. in Computers in Biology and Medicine. 2015;59:19-29.
doi:10.1016/j.compbiomed.2015.01.009 .

Hedrih, Andjelka, Lazarević, Mihailo, Mitrović-Jovanović, Ana, "Influence of sperm impact angle on successful fertilization through mZP oscillatory spherical net model" in Computers in Biology and Medicine, 59 (2015):19-29,
https://doi.org/10.1016/j.compbiomed.2015.01.009 . .

TY  - CONF
AU  - Hedrih, Anđelka
AU  - Lazarević, Mihailo
AU  - Mitrović-Jovanović, Ana
PY  - 2013
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/4600
AB  - The current paper proposes a model for describing mechanical phenomena that occur during the process of mammal fertilization when spermatozoa impact the surface of Zona Pellucida. Zona pellucida (ZP) is a dynamical 3D matrix that surrounds the mammalian oocyte. In the process of fertilization, sperm cell has to penetrate this structure. To describe impact of sperm
cells with velocities that are effective and those that are ineffective relative to the oscillatory behavior of ZP, the discreet continuum model in the form of spherical net model is used. Resultant trajectories of knot mass particles dynamics of mouse ZP spherical net model in the form of generalized Lussajous curves are presented. Using generalized Lussajous curves, parametric
frequency analysis of oscillatory behavior of knot material particles in the mouse ZP spherical net model is conducted. The influence of impact angles of sperm cells on corresponding knot mass particle trajectory is discussed. Favorable and unfavorable trajectories of knot mass particle motions are discussed in the context of successful fertilization.
PB  - Wiley Online Library
C3  - Proceedings of 84th Annual Meeting of the International Association of Applied Mathematics and Mechanics (GAMM 2013), 18-22 March, Novi Sad Serbia, PAMM
T1  - Parametric frequency analysis of oscillatory behavior of mouse Zona Pellucida spherical net model: cases of successful and of unsuccessful fertilization
EP  - 54
IS  - 13(1)
SP  - 53
UR  - https://hdl.handle.net/21.15107/rcub_machinery_4600
ER  - 

@conference{
author = "Hedrih, Anđelka and Lazarević, Mihailo and Mitrović-Jovanović, Ana",
year = "2013",
abstract = "The current paper proposes a model for describing mechanical phenomena that occur during the process of mammal fertilization when spermatozoa impact the surface of Zona Pellucida. Zona pellucida (ZP) is a dynamical 3D matrix that surrounds the mammalian oocyte. In the process of fertilization, sperm cell has to penetrate this structure. To describe impact of sperm
cells with velocities that are effective and those that are ineffective relative to the oscillatory behavior of ZP, the discreet continuum model in the form of spherical net model is used. Resultant trajectories of knot mass particles dynamics of mouse ZP spherical net model in the form of generalized Lussajous curves are presented. Using generalized Lussajous curves, parametric
frequency analysis of oscillatory behavior of knot material particles in the mouse ZP spherical net model is conducted. The influence of impact angles of sperm cells on corresponding knot mass particle trajectory is discussed. Favorable and unfavorable trajectories of knot mass particle motions are discussed in the context of successful fertilization.",
publisher = "Wiley Online Library",
journal = "Proceedings of 84th Annual Meeting of the International Association of Applied Mathematics and Mechanics (GAMM 2013), 18-22 March, Novi Sad Serbia, PAMM",
title = "Parametric frequency analysis of oscillatory behavior of mouse Zona Pellucida spherical net model: cases of successful and of unsuccessful fertilization",
pages = "54-53",
number = "13(1)",
url = "https://hdl.handle.net/21.15107/rcub_machinery_4600"
}

Hedrih, A., Lazarević, M.,& Mitrović-Jovanović, A.. (2013). Parametric frequency analysis of oscillatory behavior of mouse Zona Pellucida spherical net model: cases of successful and of unsuccessful fertilization. in Proceedings of 84th Annual Meeting of the International Association of Applied Mathematics and Mechanics (GAMM 2013), 18-22 March, Novi Sad Serbia, PAMM
Wiley Online Library.(13(1)), 53-54.
https://hdl.handle.net/21.15107/rcub_machinery_4600

Hedrih A, Lazarević M, Mitrović-Jovanović A. Parametric frequency analysis of oscillatory behavior of mouse Zona Pellucida spherical net model: cases of successful and of unsuccessful fertilization. in Proceedings of 84th Annual Meeting of the International Association of Applied Mathematics and Mechanics (GAMM 2013), 18-22 March, Novi Sad Serbia, PAMM. 2013;(13(1)):53-54.
https://hdl.handle.net/21.15107/rcub_machinery_4600 .

Hedrih, Anđelka, Lazarević, Mihailo, Mitrović-Jovanović, Ana, "Parametric frequency analysis of oscillatory behavior of mouse Zona Pellucida spherical net model: cases of successful and of unsuccessful fertilization" in Proceedings of 84th Annual Meeting of the International Association of Applied Mathematics and Mechanics (GAMM 2013), 18-22 March, Novi Sad Serbia, PAMM, no. 13(1) (2013):53-54,
https://hdl.handle.net/21.15107/rcub_machinery_4600 .

TY  - CONF
AU  - Hedrih, Andjelka
AU  - Lazarević, Mihailo
AU  - Mitrović-Jovanović, Ana
PY  - 2013
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/6612
AB  - The quality of a whole ejaculate is important for fertilization success. Number of
sperm with effective swimming velocity, capable to reach the oocyte and to undergo
complex adaptations within the female reproductive tract is a key determinant of male
fertilization success. According to the literature, total sperm numbers are positively
correlated to proportions of normal sperm, acrosome integrity and motile sperm and
also with gonadosomatic index.
Treating the fertilization process as an oscillatory phenomenon we use oscillatory
spherical net model of mouse Zona Pellucida (mZP) to investigate the impact of
sperm count on successful fertilization. To describe impact of number of
hyperactivated sperm cells relative to the oscillatory behaviour of mZP, the discreet
continuum model in the form of spherical net model is used. mZP is modelled as a
discrete system of material particles (corresponds to mZP glycoproteins)
interconnected with massless linear elastic elements on a manner that preserves molar
ratio of m ZP glycoproteins. According to the model, under external numerous vibroimpacts
of spermatozoa, mZP oscillatory net oscillates in forced regimes.
To estimate the influence of sperm count a numerical analysis was conducted. Using
generalized Lissajous curves, parametric frequency analysis of oscillatory behaviour
of ZP1 molecules in oscillatory model of mZP is realized. Numerical analysis
identified favourable oscillatory states of ZP1 molecules under the impact of different
number of spermatozoa with effective velocity.
We can conclude that ZP1 molecules in the mZP oscillatory model have different
oscillatory states when exposed to the external vibro -impacts of different number of
hyperactivated spermatozoa, indicated that certain number of hyperactivated
spermatozoa is necessary for reaching the favourable oscillatory state of mZP for
fertilisation.
PB  - Beograd : Udruženje za reproduktivno zdravlje
C3  - Abstract book  the 7th diczfalusy award lecture symposium on reproductive health 27 - 28. septembar 2013, Belgrade
T1  - Importance of number of hyperactivated spermatozoa  for successful fertilisation trough mechanical  oscillatory model of mouse zona pellucida
EP  - 2
SP  - 1
UR  - https://hdl.handle.net/21.15107/rcub_machinery_6612
ER  - 

@conference{
author = "Hedrih, Andjelka and Lazarević, Mihailo and Mitrović-Jovanović, Ana",
year = "2013",
abstract = "The quality of a whole ejaculate is important for fertilization success. Number of
sperm with effective swimming velocity, capable to reach the oocyte and to undergo
complex adaptations within the female reproductive tract is a key determinant of male
fertilization success. According to the literature, total sperm numbers are positively
correlated to proportions of normal sperm, acrosome integrity and motile sperm and
also with gonadosomatic index.
Treating the fertilization process as an oscillatory phenomenon we use oscillatory
spherical net model of mouse Zona Pellucida (mZP) to investigate the impact of
sperm count on successful fertilization. To describe impact of number of
hyperactivated sperm cells relative to the oscillatory behaviour of mZP, the discreet
continuum model in the form of spherical net model is used. mZP is modelled as a
discrete system of material particles (corresponds to mZP glycoproteins)
interconnected with massless linear elastic elements on a manner that preserves molar
ratio of m ZP glycoproteins. According to the model, under external numerous vibroimpacts
of spermatozoa, mZP oscillatory net oscillates in forced regimes.
To estimate the influence of sperm count a numerical analysis was conducted. Using
generalized Lissajous curves, parametric frequency analysis of oscillatory behaviour
of ZP1 molecules in oscillatory model of mZP is realized. Numerical analysis
identified favourable oscillatory states of ZP1 molecules under the impact of different
number of spermatozoa with effective velocity.
We can conclude that ZP1 molecules in the mZP oscillatory model have different
oscillatory states when exposed to the external vibro -impacts of different number of
hyperactivated spermatozoa, indicated that certain number of hyperactivated
spermatozoa is necessary for reaching the favourable oscillatory state of mZP for
fertilisation.",
publisher = "Beograd : Udruženje za reproduktivno zdravlje",
journal = "Abstract book  the 7th diczfalusy award lecture symposium on reproductive health 27 - 28. septembar 2013, Belgrade",
title = "Importance of number of hyperactivated spermatozoa  for successful fertilisation trough mechanical  oscillatory model of mouse zona pellucida",
pages = "2-1",
url = "https://hdl.handle.net/21.15107/rcub_machinery_6612"
}

Hedrih, A., Lazarević, M.,& Mitrović-Jovanović, A.. (2013). Importance of number of hyperactivated spermatozoa  for successful fertilisation trough mechanical  oscillatory model of mouse zona pellucida. in Abstract book  the 7th diczfalusy award lecture symposium on reproductive health 27 - 28. septembar 2013, Belgrade
Beograd : Udruženje za reproduktivno zdravlje., 1-2.
https://hdl.handle.net/21.15107/rcub_machinery_6612

Hedrih A, Lazarević M, Mitrović-Jovanović A. Importance of number of hyperactivated spermatozoa  for successful fertilisation trough mechanical  oscillatory model of mouse zona pellucida. in Abstract book  the 7th diczfalusy award lecture symposium on reproductive health 27 - 28. septembar 2013, Belgrade. 2013;:1-2.
https://hdl.handle.net/21.15107/rcub_machinery_6612 .

Hedrih, Andjelka, Lazarević, Mihailo, Mitrović-Jovanović, Ana, "Importance of number of hyperactivated spermatozoa  for successful fertilisation trough mechanical  oscillatory model of mouse zona pellucida" in Abstract book  the 7th diczfalusy award lecture symposium on reproductive health 27 - 28. septembar 2013, Belgrade (2013):1-2,
https://hdl.handle.net/21.15107/rcub_machinery_6612 .