Review of the article Assessment of Reproductive Hormones among Infertile Sudanese Males in Khartoum State, verified by Publons, Web of Science
Апстракт
Background: Infertility seems to be a great worldwide problem. Male infertility is a multifaceted state and overlaps a lot factors and affects infertility in about 8–5 % of the people in the world and the man is responsible for 40% of these cases. The FSH, LH and testosterone evaluation is useful in the management of male infertility. For initiation of spermatogenesis and maturation of spermatozoa, FSH is necessary. In the infertile men, higher concentration of FSH is considered to be a reliable indicator of germinal epithelial damage, and was shown to be associated with azoospermia and severe oligozoospermia
Objective: The aim of the study is to analyze the levels of reproductive hormones among different groups of infertile patients.
Materials and method: This is a facility based study, conducted in Reproductive Care Center in Almuk Nemer Street in Khartoum state. Which include 160 serum samples collected from normozoospermic, oligoathenospermic, and azoospermic men and clinical inf...ormation collected by the use of questionnaire. The concentrations of reproductive hormones were measured by using a full automated tosoh AIA360 analyzer, then the data was analyzed using the statistical software package SPSS version 17.
Result: The results showed that the serum levels of prolactin and FSH is statistically significant increase in patient with azoospermia and oligoasthenospermia as compared to control group, with (p .value < 0.05), and the serum level of LH is statistically significant increase in patient with azoospermia and insignificant increase in patient with oligoasthenospermia as compared to control group, with p .value (0.000 and 0.232), respectively. And the serum level of testosterone is statistically insignificant decrease in patient with azoospermia and insignificantly increase in patient with oligoasthenospermia as compared to control group, with p .value (0.88 and 0.129), respectively. The results also showed statistically insignificant decrease in the serum levels of testosterone and prolactin in azoospermia when compared with oligoathenospermia, with p. value (0.227 and 0.959) respectively. And showed statistically significant increase in the serum levels of FSH and LH in azoospermia when compared with oligoathenospermia, with p. value (0.002 and 0.007) respectively.
Conclusion: The level of serum testosterone was insignificantly decreased in patients with azoospermia and insignificantly increased in patients with oligoasthenospermia when compared with control group. The serum levels of prolactin and FSH was significantly increased in patients with azoospermia and oligoasthenospermia when compared with control group. And the serum level of LH in increased significantly in patients with azoospermia and insignificantly in oligoasthenospermia when compared with control group. The serum levels of testosterone and prolactin is insignificant decrease in azoospermia when compared with oligoathenospermia, and the serum levels of FSH and LH is significant increase in azoospermia when compared with oligoathenospermia.
Извор:
Asian Journal of Research and Reports in Endocrinology, 2023, 1/Ms_AJRRE_96747-5Колекције
Институција/група
Mašinski fakultetTY - JOUR AU - Jovanović, Tamara PY - 2023 UR - www.journalajrre.com UR - https://machinery.mas.bg.ac.rs/handle/123456789/6369 AB - Background: Infertility seems to be a great worldwide problem. Male infertility is a multifaceted state and overlaps a lot factors and affects infertility in about 8–5 % of the people in the world and the man is responsible for 40% of these cases. The FSH, LH and testosterone evaluation is useful in the management of male infertility. For initiation of spermatogenesis and maturation of spermatozoa, FSH is necessary. In the infertile men, higher concentration of FSH is considered to be a reliable indicator of germinal epithelial damage, and was shown to be associated with azoospermia and severe oligozoospermia Objective: The aim of the study is to analyze the levels of reproductive hormones among different groups of infertile patients. Materials and method: This is a facility based study, conducted in Reproductive Care Center in Almuk Nemer Street in Khartoum state. Which include 160 serum samples collected from normozoospermic, oligoathenospermic, and azoospermic men and clinical information collected by the use of questionnaire. The concentrations of reproductive hormones were measured by using a full automated tosoh AIA360 analyzer, then the data was analyzed using the statistical software package SPSS version 17. Result: The results showed that the serum levels of prolactin and FSH is statistically significant increase in patient with azoospermia and oligoasthenospermia as compared to control group, with (p .value < 0.05), and the serum level of LH is statistically significant increase in patient with azoospermia and insignificant increase in patient with oligoasthenospermia as compared to control group, with p .value (0.000 and 0.232), respectively. And the serum level of testosterone is statistically insignificant decrease in patient with azoospermia and insignificantly increase in patient with oligoasthenospermia as compared to control group, with p .value (0.88 and 0.129), respectively. The results also showed statistically insignificant decrease in the serum levels of testosterone and prolactin in azoospermia when compared with oligoathenospermia, with p. value (0.227 and 0.959) respectively. And showed statistically significant increase in the serum levels of FSH and LH in azoospermia when compared with oligoathenospermia, with p. value (0.002 and 0.007) respectively. Conclusion: The level of serum testosterone was insignificantly decreased in patients with azoospermia and insignificantly increased in patients with oligoasthenospermia when compared with control group. The serum levels of prolactin and FSH was significantly increased in patients with azoospermia and oligoasthenospermia when compared with control group. And the serum level of LH in increased significantly in patients with azoospermia and insignificantly in oligoasthenospermia when compared with control group. The serum levels of testosterone and prolactin is insignificant decrease in azoospermia when compared with oligoathenospermia, and the serum levels of FSH and LH is significant increase in azoospermia when compared with oligoathenospermia. T2 - Asian Journal of Research and Reports in Endocrinology T1 - Review of the article Assessment of Reproductive Hormones among Infertile Sudanese Males in Khartoum State, verified by Publons, Web of Science EP - 5 SP - 1/Ms_AJRRE_96747 UR - https://hdl.handle.net/21.15107/rcub_machinery_6369 ER -
@article{ author = "Jovanović, Tamara", year = "2023", abstract = "Background: Infertility seems to be a great worldwide problem. Male infertility is a multifaceted state and overlaps a lot factors and affects infertility in about 8–5 % of the people in the world and the man is responsible for 40% of these cases. The FSH, LH and testosterone evaluation is useful in the management of male infertility. For initiation of spermatogenesis and maturation of spermatozoa, FSH is necessary. In the infertile men, higher concentration of FSH is considered to be a reliable indicator of germinal epithelial damage, and was shown to be associated with azoospermia and severe oligozoospermia Objective: The aim of the study is to analyze the levels of reproductive hormones among different groups of infertile patients. Materials and method: This is a facility based study, conducted in Reproductive Care Center in Almuk Nemer Street in Khartoum state. Which include 160 serum samples collected from normozoospermic, oligoathenospermic, and azoospermic men and clinical information collected by the use of questionnaire. The concentrations of reproductive hormones were measured by using a full automated tosoh AIA360 analyzer, then the data was analyzed using the statistical software package SPSS version 17. Result: The results showed that the serum levels of prolactin and FSH is statistically significant increase in patient with azoospermia and oligoasthenospermia as compared to control group, with (p .value < 0.05), and the serum level of LH is statistically significant increase in patient with azoospermia and insignificant increase in patient with oligoasthenospermia as compared to control group, with p .value (0.000 and 0.232), respectively. And the serum level of testosterone is statistically insignificant decrease in patient with azoospermia and insignificantly increase in patient with oligoasthenospermia as compared to control group, with p .value (0.88 and 0.129), respectively. The results also showed statistically insignificant decrease in the serum levels of testosterone and prolactin in azoospermia when compared with oligoathenospermia, with p. value (0.227 and 0.959) respectively. And showed statistically significant increase in the serum levels of FSH and LH in azoospermia when compared with oligoathenospermia, with p. value (0.002 and 0.007) respectively. Conclusion: The level of serum testosterone was insignificantly decreased in patients with azoospermia and insignificantly increased in patients with oligoasthenospermia when compared with control group. The serum levels of prolactin and FSH was significantly increased in patients with azoospermia and oligoasthenospermia when compared with control group. And the serum level of LH in increased significantly in patients with azoospermia and insignificantly in oligoasthenospermia when compared with control group. The serum levels of testosterone and prolactin is insignificant decrease in azoospermia when compared with oligoathenospermia, and the serum levels of FSH and LH is significant increase in azoospermia when compared with oligoathenospermia.", journal = "Asian Journal of Research and Reports in Endocrinology", title = "Review of the article Assessment of Reproductive Hormones among Infertile Sudanese Males in Khartoum State, verified by Publons, Web of Science", pages = "5-1/Ms_AJRRE_96747", url = "https://hdl.handle.net/21.15107/rcub_machinery_6369" }
Jovanović, T.. (2023). Review of the article Assessment of Reproductive Hormones among Infertile Sudanese Males in Khartoum State, verified by Publons, Web of Science. in Asian Journal of Research and Reports in Endocrinology, 1/Ms_AJRRE_96747-5. https://hdl.handle.net/21.15107/rcub_machinery_6369
Jovanović T. Review of the article Assessment of Reproductive Hormones among Infertile Sudanese Males in Khartoum State, verified by Publons, Web of Science. in Asian Journal of Research and Reports in Endocrinology. 2023;:1/Ms_AJRRE_96747-5. https://hdl.handle.net/21.15107/rcub_machinery_6369 .
Jovanović, Tamara, "Review of the article Assessment of Reproductive Hormones among Infertile Sudanese Males in Khartoum State, verified by Publons, Web of Science" in Asian Journal of Research and Reports in Endocrinology (2023):1/Ms_AJRRE_96747-5, https://hdl.handle.net/21.15107/rcub_machinery_6369 .