Review of the article The Effects of Aqueous Extract of Garlic on Bacterial Keratitis, verified by Publons, Web of Science
Članak u časopisu (Recenzirana verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The use of Allium Sativum (garlic) for the treatment of various microbial infections of the human body has been an age long practice. However very little is known about the effectiveness of garlic extracts in the treatment of ocular bacterial infections. The aim of this study was to demonstrate the effectiveness of aqueous garlic extracts against bacterial infections of the cornea in albino rats. For this study, two strains of Staphylococcus aureus and Psuedomonas aeruginosa were used to as the bacterial organisms. The study was carried out both in vitro and in vivo. The in vitro study involved the measurement of zones of inhibition of the garlic extract on the bacterial organisms and the minimum inhibitory concentrations of the aqueous garlic extract to the two bacterial organisms. The in vivo study involved the infection of the corneas of forty albino rats with the microorganisms. Two concentrations of the aqueous garlic; 113mg/ml and 56.5mg/ml were used and compared to 0.3% Ciproflo...xacin eye drop. The treatment lasted for a period of ten days and until the infection was resolved. Colony counts were taken after each day of treatment for the period of ten days. The data obtained was analysed using the Analysis of Variance at a significance level of P<0.05 and tested against the research hypothesis. From the results, it was discovered that the two concentrations of the aqueous garlic extracts were effective in treating the keratitis caused by the two microorganisms. However when they were compared to 0.3% Ciprofloxacin eye drop, it was noticed that the Ciprofloxacin was more effective in treating the microbial keratitis than the aqueous garlic extracts.
Izvor:
Asian Journal of Research in Infectious Diseases, 2023, 1/Ms_AJRID_95848-14Kolekcije
Institucija/grupa
Mašinski fakultetTY - JOUR AU - Jovanović, Tamara PY - 2023 UR - https://machinery.mas.bg.ac.rs/handle/123456789/6365 AB - The use of Allium Sativum (garlic) for the treatment of various microbial infections of the human body has been an age long practice. However very little is known about the effectiveness of garlic extracts in the treatment of ocular bacterial infections. The aim of this study was to demonstrate the effectiveness of aqueous garlic extracts against bacterial infections of the cornea in albino rats. For this study, two strains of Staphylococcus aureus and Psuedomonas aeruginosa were used to as the bacterial organisms. The study was carried out both in vitro and in vivo. The in vitro study involved the measurement of zones of inhibition of the garlic extract on the bacterial organisms and the minimum inhibitory concentrations of the aqueous garlic extract to the two bacterial organisms. The in vivo study involved the infection of the corneas of forty albino rats with the microorganisms. Two concentrations of the aqueous garlic; 113mg/ml and 56.5mg/ml were used and compared to 0.3% Ciprofloxacin eye drop. The treatment lasted for a period of ten days and until the infection was resolved. Colony counts were taken after each day of treatment for the period of ten days. The data obtained was analysed using the Analysis of Variance at a significance level of P<0.05 and tested against the research hypothesis. From the results, it was discovered that the two concentrations of the aqueous garlic extracts were effective in treating the keratitis caused by the two microorganisms. However when they were compared to 0.3% Ciprofloxacin eye drop, it was noticed that the Ciprofloxacin was more effective in treating the microbial keratitis than the aqueous garlic extracts. T2 - Asian Journal of Research in Infectious Diseases T1 - Review of the article The Effects of Aqueous Extract of Garlic on Bacterial Keratitis, verified by Publons, Web of Science EP - 14 SP - 1/Ms_AJRID_95848 UR - https://hdl.handle.net/21.15107/rcub_machinery_6365 ER -
@article{ author = "Jovanović, Tamara", year = "2023", abstract = "The use of Allium Sativum (garlic) for the treatment of various microbial infections of the human body has been an age long practice. However very little is known about the effectiveness of garlic extracts in the treatment of ocular bacterial infections. The aim of this study was to demonstrate the effectiveness of aqueous garlic extracts against bacterial infections of the cornea in albino rats. For this study, two strains of Staphylococcus aureus and Psuedomonas aeruginosa were used to as the bacterial organisms. The study was carried out both in vitro and in vivo. The in vitro study involved the measurement of zones of inhibition of the garlic extract on the bacterial organisms and the minimum inhibitory concentrations of the aqueous garlic extract to the two bacterial organisms. The in vivo study involved the infection of the corneas of forty albino rats with the microorganisms. Two concentrations of the aqueous garlic; 113mg/ml and 56.5mg/ml were used and compared to 0.3% Ciprofloxacin eye drop. The treatment lasted for a period of ten days and until the infection was resolved. Colony counts were taken after each day of treatment for the period of ten days. The data obtained was analysed using the Analysis of Variance at a significance level of P<0.05 and tested against the research hypothesis. From the results, it was discovered that the two concentrations of the aqueous garlic extracts were effective in treating the keratitis caused by the two microorganisms. However when they were compared to 0.3% Ciprofloxacin eye drop, it was noticed that the Ciprofloxacin was more effective in treating the microbial keratitis than the aqueous garlic extracts.", journal = "Asian Journal of Research in Infectious Diseases", title = "Review of the article The Effects of Aqueous Extract of Garlic on Bacterial Keratitis, verified by Publons, Web of Science", pages = "14-1/Ms_AJRID_95848", url = "https://hdl.handle.net/21.15107/rcub_machinery_6365" }
Jovanović, T.. (2023). Review of the article The Effects of Aqueous Extract of Garlic on Bacterial Keratitis, verified by Publons, Web of Science. in Asian Journal of Research in Infectious Diseases, 1/Ms_AJRID_95848-14. https://hdl.handle.net/21.15107/rcub_machinery_6365
Jovanović T. Review of the article The Effects of Aqueous Extract of Garlic on Bacterial Keratitis, verified by Publons, Web of Science. in Asian Journal of Research in Infectious Diseases. 2023;:1/Ms_AJRID_95848-14. https://hdl.handle.net/21.15107/rcub_machinery_6365 .
Jovanović, Tamara, "Review of the article The Effects of Aqueous Extract of Garlic on Bacterial Keratitis, verified by Publons, Web of Science" in Asian Journal of Research in Infectious Diseases (2023):1/Ms_AJRID_95848-14, https://hdl.handle.net/21.15107/rcub_machinery_6365 .