Opto-magnetic imaging spectroscopy in characterization of the tissues during hyperbaric oxygen therapy
Abstract
Background/aim: Opto-magnetic imaging spectroscopy (OMIS) was used as a novel method to detemine tissue molecular conformation changes during hyperbaric oxygen (HBO) therapy. The aim of this study was to examine the usefulness of OMIS for the assessment of HBO therapy effectiveness on the diseased tissue.
Methods: OMIS is concerned with obtaining paramagnetic/diamagnetic properties of materials, related to the presence of unpaired/paired electrons based on their interaction with visible light. The basic tool is light of wavelength in the range between 400 nm and 700 nm and its interaction with tissue. The study included 22 subjects: 16 angiopathy patients and 6 healthy subjects as the control group. OMIS was used with patients on the 1st, 10th and 20th session and with the control group on the 1st, 10th and 20th day without HBO therapy in between.
Results: The obtained results showed that healthy skin of all the control group subjects had the same shape curve. In the angiopathy p...atient group, before the first session OMIS showed tissue disorder and after the last session results resembled more closely the results in healthy tissue. The differences in the tissue state in the angiopathy group before each session were noticeable, showing normalized tissue under the influence of HBO.
Conclusion: The results show that OMIS could be used as a diagnostic tool for detection of the tissue state before and after the HBO therapy.
Keywords:
hyperbaric oxygenation / tissues / spectrum analysis / biomedical engineering / methods / optical imagingSource:
Vojnosanitetski pregled, 2015, 72, 922-927Publisher:
- Serbian Army
Funding / projects:
- Development of methods and techniques for early diagnostic of cervical, colon, oral cavity cancer and melanoma based on a digital image and excitation-emission spectrum in visible and infrared domain (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41006)
URI
https://www.doiserbia.nb.rs/Article.aspx?id=0042-84501500077S#.ZA0JgHZKhEZhttps://machinery.mas.bg.ac.rs/handle/123456789/5846
Collections
Institution/Community
Mašinski fakultetTY - JOUR AU - Sedlar, Mariana AU - Nikolić, Gorana AU - Dragičević, Aleksandra AU - Koruga, Đuro PY - 2015 UR - https://www.doiserbia.nb.rs/Article.aspx?id=0042-84501500077S#.ZA0JgHZKhEZ UR - https://machinery.mas.bg.ac.rs/handle/123456789/5846 AB - Background/aim: Opto-magnetic imaging spectroscopy (OMIS) was used as a novel method to detemine tissue molecular conformation changes during hyperbaric oxygen (HBO) therapy. The aim of this study was to examine the usefulness of OMIS for the assessment of HBO therapy effectiveness on the diseased tissue. Methods: OMIS is concerned with obtaining paramagnetic/diamagnetic properties of materials, related to the presence of unpaired/paired electrons based on their interaction with visible light. The basic tool is light of wavelength in the range between 400 nm and 700 nm and its interaction with tissue. The study included 22 subjects: 16 angiopathy patients and 6 healthy subjects as the control group. OMIS was used with patients on the 1st, 10th and 20th session and with the control group on the 1st, 10th and 20th day without HBO therapy in between. Results: The obtained results showed that healthy skin of all the control group subjects had the same shape curve. In the angiopathy patient group, before the first session OMIS showed tissue disorder and after the last session results resembled more closely the results in healthy tissue. The differences in the tissue state in the angiopathy group before each session were noticeable, showing normalized tissue under the influence of HBO. Conclusion: The results show that OMIS could be used as a diagnostic tool for detection of the tissue state before and after the HBO therapy. PB - Serbian Army T2 - Vojnosanitetski pregled T1 - Opto-magnetic imaging spectroscopy in characterization of the tissues during hyperbaric oxygen therapy EP - 927 SP - 922 VL - 72 DO - 10.2298/vsp140610077s ER -
@article{ author = "Sedlar, Mariana and Nikolić, Gorana and Dragičević, Aleksandra and Koruga, Đuro", year = "2015", abstract = "Background/aim: Opto-magnetic imaging spectroscopy (OMIS) was used as a novel method to detemine tissue molecular conformation changes during hyperbaric oxygen (HBO) therapy. The aim of this study was to examine the usefulness of OMIS for the assessment of HBO therapy effectiveness on the diseased tissue. Methods: OMIS is concerned with obtaining paramagnetic/diamagnetic properties of materials, related to the presence of unpaired/paired electrons based on their interaction with visible light. The basic tool is light of wavelength in the range between 400 nm and 700 nm and its interaction with tissue. The study included 22 subjects: 16 angiopathy patients and 6 healthy subjects as the control group. OMIS was used with patients on the 1st, 10th and 20th session and with the control group on the 1st, 10th and 20th day without HBO therapy in between. Results: The obtained results showed that healthy skin of all the control group subjects had the same shape curve. In the angiopathy patient group, before the first session OMIS showed tissue disorder and after the last session results resembled more closely the results in healthy tissue. The differences in the tissue state in the angiopathy group before each session were noticeable, showing normalized tissue under the influence of HBO. Conclusion: The results show that OMIS could be used as a diagnostic tool for detection of the tissue state before and after the HBO therapy.", publisher = "Serbian Army", journal = "Vojnosanitetski pregled", title = "Opto-magnetic imaging spectroscopy in characterization of the tissues during hyperbaric oxygen therapy", pages = "927-922", volume = "72", doi = "10.2298/vsp140610077s" }
Sedlar, M., Nikolić, G., Dragičević, A.,& Koruga, Đ.. (2015). Opto-magnetic imaging spectroscopy in characterization of the tissues during hyperbaric oxygen therapy. in Vojnosanitetski pregled Serbian Army., 72, 922-927. https://doi.org/10.2298/vsp140610077s
Sedlar M, Nikolić G, Dragičević A, Koruga Đ. Opto-magnetic imaging spectroscopy in characterization of the tissues during hyperbaric oxygen therapy. in Vojnosanitetski pregled. 2015;72:922-927. doi:10.2298/vsp140610077s .
Sedlar, Mariana, Nikolić, Gorana, Dragičević, Aleksandra, Koruga, Đuro, "Opto-magnetic imaging spectroscopy in characterization of the tissues during hyperbaric oxygen therapy" in Vojnosanitetski pregled, 72 (2015):922-927, https://doi.org/10.2298/vsp140610077s . .