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dc.creatorMiljković, Suzana
dc.creatorJeftić, Branislava
dc.creatorŠarac, Dušan
dc.creatorMatović, Valentina
dc.creatorSlavković, Marija
dc.creatorKoruga, Đuro
dc.date.accessioned2022-09-19T19:02:54Z
dc.date.available2022-09-19T19:02:54Z
dc.date.issued2020
dc.identifier.issn1473-2130
dc.identifier.urihttps://machinery.mas.bg.ac.rs/handle/123456789/3343
dc.description.abstractBackground Fullerene water complex establishes the optimal order and function of biomolecules in natural, biophysical way by transducing the signal through water hydrogen bonds to biomolecules. Objectives This paper considers the effects of the patented hyper-harmonized-hydroxylated fullerene water complex (3HFWC) on biophysical properties of the skin collagen molecules. Method Optomagnetic imaging spectroscopy (OMIS) has been used for the analysis of the biophysical skin properties (diamagnetic/paramagnetic) after applying three groups of different cosmetic products. Tested cosmetic products were prepared by replacing the active ingredients with 3HFWC or with water in four commercial products. The original commercial creams and their vehiculums with water added served as control groups. Data were statistically analyzed using paired t test in R software. Results t Test gave statistically significant results for all of the products with 3HFWC, while within the control group, only body lotion and hand cream did show statistically significant results (P lt 0.05). Significant improvements in abundance and quality of collagen in the dermis were achieved with body lotion with 3HFWC (p(+)/p(-)ranged from 0.82 to 0.97). While body lotion vehiculum made collagen-water interaction more stable (p(+)/p(-)ranged from 0.3 to 0.55), hand cream with 3HFWC made it more dynamic (p(+)/p(-)ranged from 0.63 to 0.49). Body lotion vehiculum improved the compactness of the dermis (p(+)/p(-)ranged from 0.2 to 1.03), as well as commercial hand cream (p(+)/p(-) ranged from 0.28 to 0.85). Conclusion Compared to the control groups, cosmetic products with 3HFWC demonstrated positive effects on the biophysical properties of the skin. Increased paramagnetic properties are linked to more unpaired electrons, their faster movement, and, finally, better signal transduction. Thus, products with 3HFWC could enable faster regeneration of collagen and prompt skin reaction to the negative environmental influences.en
dc.publisherWiley, Hoboken
dc.rightsrestrictedAccess
dc.sourceJournal of Cosmetic Dermatology
dc.subjectskin careen
dc.subjectOMISen
dc.subjectfunctionalized fullerenesen
dc.subjectcollagenen
dc.titleInfluence of hyper-harmonized fullerene water complex on collagen quality and skin functionen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage501
dc.citation.issue2
dc.citation.other19(2): 494-501
dc.citation.rankM22
dc.citation.spage494
dc.citation.volume19
dc.identifier.doi10.1111/jocd.12999
dc.identifier.pmid31141275
dc.identifier.scopus2-s2.0-85066508342
dc.identifier.wos000509508100033
dc.type.versionpublishedVersion


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Приказ основних података о документу