Influence of the sperm velocity on fertilization capacity in the oscillatory model of mouse zona pellucida
Apstrakt
Considering the fertilization process as an oscillatory phenomenon, based on mechanotransduction theory of sperm–oocyte interaction, influence of sperm velocity and their specific arrangement on outer surface of oocyte- Zona pellucida (ZP) relative to the oscillatory behavior of ZP was studied using discrete continuum oscillatory spherical net model of mouse ZP. For the calculated favorable impact angles of spermatozoa by using generalized Lissajous
curves, a parametric frequency analysis of oscillatory behavior of the knot molecules in the mouse ZP spherical net model is conducted. In order to mimic successful fertilization in physiological conditions in this numerical experiment, velocities of the progressive and hyperactivated spermatozoa were used. The resultant trajectories of knot molecules in mouse ZP (mZP) spherical net model,in the form of generalized Lissajous curves, are presented. Influences of the
sperm velocity and its arrangement on the resultant trajectory of the corr...esponding
knot molecules are discussed. Component displacements in the meridian and circular directions of the knot molecules of ZP are in the form of multi-frequency oscillations. Symmetrical arrangements of spermatozoa having effective velocities are more favorable for achieving a favorable oscillatory
multi-frequency state of mZP for a successful fertilization. Determining the optimal parameters of spermatozoa impact that will induce a ZP favorable oscillatory state opens the possibilities for more complete explanation of the fertilization process.
Ključne reči:
Zona pellucida / Discrete oscillatory spherical net model / Oscillations / Lissajous curves / Sperm velocity / Sperm arrangementIzvor:
Advanced Problems in Mechanics Proceedings of the XLVII International Summer School-Conference “Advanced Problems in Mechanics”, June 24-29, 2019, St. Petersburg, Russia, 2020, 1-21Izdavač:
- Springer Nature Switzerland AG 2020
Finansiranje / projekti:
- Razvoj novih metoda i tehnika za ranu dijagnostiku kancera grlića materice, debelog creva, usne duplje i melanoma na bazi digitalne slike i ekscitaciono-emisionih spektara u vidljivom i infracrvenom domenu (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-41006)
- Dinamika hibridnih sistema složenih struktura. Mehanika materijala (RS-MESTD-Basic Research (BR or ON)-174001)
Kolekcije
Institucija/grupa
Mašinski fakultetTY - CONF AU - Hedrih, Andjelka AU - Mitrovic-Jovanovic, Ana AU - Lazarević, Mihailo PY - 2020 UR - 10.1007/978-3-030-49882-5 UR - https://machinery.mas.bg.ac.rs/handle/123456789/6447 AB - Considering the fertilization process as an oscillatory phenomenon, based on mechanotransduction theory of sperm–oocyte interaction, influence of sperm velocity and their specific arrangement on outer surface of oocyte- Zona pellucida (ZP) relative to the oscillatory behavior of ZP was studied using discrete continuum oscillatory spherical net model of mouse ZP. For the calculated favorable impact angles of spermatozoa by using generalized Lissajous curves, a parametric frequency analysis of oscillatory behavior of the knot molecules in the mouse ZP spherical net model is conducted. In order to mimic successful fertilization in physiological conditions in this numerical experiment, velocities of the progressive and hyperactivated spermatozoa were used. The resultant trajectories of knot molecules in mouse ZP (mZP) spherical net model,in the form of generalized Lissajous curves, are presented. Influences of the sperm velocity and its arrangement on the resultant trajectory of the corresponding knot molecules are discussed. Component displacements in the meridian and circular directions of the knot molecules of ZP are in the form of multi-frequency oscillations. Symmetrical arrangements of spermatozoa having effective velocities are more favorable for achieving a favorable oscillatory multi-frequency state of mZP for a successful fertilization. Determining the optimal parameters of spermatozoa impact that will induce a ZP favorable oscillatory state opens the possibilities for more complete explanation of the fertilization process. PB - Springer Nature Switzerland AG 2020 C3 - Advanced Problems in Mechanics Proceedings of the XLVII International Summer School-Conference “Advanced Problems in Mechanics”, June 24-29, 2019, St. Petersburg, Russia T1 - Influence of the sperm velocity on fertilization capacity in the oscillatory model of mouse zona pellucida EP - 21 SP - 1 UR - https://hdl.handle.net/21.15107/rcub_machinery_6447 ER -
@conference{ author = "Hedrih, Andjelka and Mitrovic-Jovanovic, Ana and Lazarević, Mihailo", year = "2020", abstract = "Considering the fertilization process as an oscillatory phenomenon, based on mechanotransduction theory of sperm–oocyte interaction, influence of sperm velocity and their specific arrangement on outer surface of oocyte- Zona pellucida (ZP) relative to the oscillatory behavior of ZP was studied using discrete continuum oscillatory spherical net model of mouse ZP. For the calculated favorable impact angles of spermatozoa by using generalized Lissajous curves, a parametric frequency analysis of oscillatory behavior of the knot molecules in the mouse ZP spherical net model is conducted. In order to mimic successful fertilization in physiological conditions in this numerical experiment, velocities of the progressive and hyperactivated spermatozoa were used. The resultant trajectories of knot molecules in mouse ZP (mZP) spherical net model,in the form of generalized Lissajous curves, are presented. Influences of the sperm velocity and its arrangement on the resultant trajectory of the corresponding knot molecules are discussed. Component displacements in the meridian and circular directions of the knot molecules of ZP are in the form of multi-frequency oscillations. Symmetrical arrangements of spermatozoa having effective velocities are more favorable for achieving a favorable oscillatory multi-frequency state of mZP for a successful fertilization. Determining the optimal parameters of spermatozoa impact that will induce a ZP favorable oscillatory state opens the possibilities for more complete explanation of the fertilization process.", publisher = "Springer Nature Switzerland AG 2020", journal = "Advanced Problems in Mechanics Proceedings of the XLVII International Summer School-Conference “Advanced Problems in Mechanics”, June 24-29, 2019, St. Petersburg, Russia", title = "Influence of the sperm velocity on fertilization capacity in the oscillatory model of mouse zona pellucida", pages = "21-1", url = "https://hdl.handle.net/21.15107/rcub_machinery_6447" }
Hedrih, A., Mitrovic-Jovanovic, A.,& Lazarević, M.. (2020). Influence of the sperm velocity on fertilization capacity in the oscillatory model of mouse zona pellucida. in Advanced Problems in Mechanics Proceedings of the XLVII International Summer School-Conference “Advanced Problems in Mechanics”, June 24-29, 2019, St. Petersburg, Russia Springer Nature Switzerland AG 2020., 1-21. https://hdl.handle.net/21.15107/rcub_machinery_6447
Hedrih A, Mitrovic-Jovanovic A, Lazarević M. Influence of the sperm velocity on fertilization capacity in the oscillatory model of mouse zona pellucida. in Advanced Problems in Mechanics Proceedings of the XLVII International Summer School-Conference “Advanced Problems in Mechanics”, June 24-29, 2019, St. Petersburg, Russia. 2020;:1-21. https://hdl.handle.net/21.15107/rcub_machinery_6447 .
Hedrih, Andjelka, Mitrovic-Jovanovic, Ana, Lazarević, Mihailo, "Influence of the sperm velocity on fertilization capacity in the oscillatory model of mouse zona pellucida" in Advanced Problems in Mechanics Proceedings of the XLVII International Summer School-Conference “Advanced Problems in Mechanics”, June 24-29, 2019, St. Petersburg, Russia (2020):1-21, https://hdl.handle.net/21.15107/rcub_machinery_6447 .