Multi-layer oscillatory spherical net model of mouse zona Pelucida

Abstract

Zona Pelucida (ZP) is multi-layer mesh-like 3D structure that surrounds mammalian eggs. One of its biological functions is selectivity regarding sperm penetration. Oscillatory spherical net model of mZP is suitable for explain initial stadium of sperm penetration. This model is single-layer model. On a basis of single-layered oscillatory spherical net model of mZP we proposed improved double layer models. Due to visco-elastic properties of ZP and its importance for mechanism of sperm penetration double layered oscillatory net model of mZP has fractional order properties. Oscillatory behavior of this double-layered system is discussed.