TY  - JOUR
AU  - Simić-Krstić, Jovana
AU  - Kalauzi, Aleksandar J.
AU  - Ribar, Srđan
AU  - Matija, Lidija
AU  - Misević, Gradimir N.
PY  - 2014
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/1923
AB  - A non-invasive bioimpedance spectroscopy (BIS) and Cole-Cole impedance model parameters (R-0, R-infinity, tau and alpha) were used to analyze electrical properties of intact and stripped human skin for both gender subjects divided into younger and older age groups. R-0, R-infinity and tau significantly increased while a significantly decreased with age in stripped skin for both genders (p  lt  0.031). Using pooled data with respect to age, gender and skin stripping, R-0, R-infinity and t values were shown to increase with age (p  lt  0.0034), R-0, tau and alpha were different between genders (p  lt  0.024) and R-0, R-infinity and tau decreased with skin stripping (p  lt  0.000008). All of four Cole-Cole parameters were age dependent with specific differences observed for genders and intact and stripped skin layers. Therefore, Cole-Cole parameters, obtained by non-invasive BIS measurements, are a new type of age dependent biomarkers.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Experimental Gerontology
T1  - Electrical properties of human skin as aging biomarkers
EP  - 167
SP  - 163
VL  - 57
DO  - 10.1016/j.exger.2014.06.001
ER  - 

@article{
author = "Simić-Krstić, Jovana and Kalauzi, Aleksandar J. and Ribar, Srđan and Matija, Lidija and Misević, Gradimir N.",
year = "2014",
abstract = "A non-invasive bioimpedance spectroscopy (BIS) and Cole-Cole impedance model parameters (R-0, R-infinity, tau and alpha) were used to analyze electrical properties of intact and stripped human skin for both gender subjects divided into younger and older age groups. R-0, R-infinity and tau significantly increased while a significantly decreased with age in stripped skin for both genders (p  lt  0.031). Using pooled data with respect to age, gender and skin stripping, R-0, R-infinity and t values were shown to increase with age (p  lt  0.0034), R-0, tau and alpha were different between genders (p  lt  0.024) and R-0, R-infinity and tau decreased with skin stripping (p  lt  0.000008). All of four Cole-Cole parameters were age dependent with specific differences observed for genders and intact and stripped skin layers. Therefore, Cole-Cole parameters, obtained by non-invasive BIS measurements, are a new type of age dependent biomarkers.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Experimental Gerontology",
title = "Electrical properties of human skin as aging biomarkers",
pages = "167-163",
volume = "57",
doi = "10.1016/j.exger.2014.06.001"
}

Simić-Krstić, J., Kalauzi, A. J., Ribar, S., Matija, L.,& Misević, G. N.. (2014). Electrical properties of human skin as aging biomarkers. in Experimental Gerontology
Pergamon-Elsevier Science Ltd, Oxford., 57, 163-167.
https://doi.org/10.1016/j.exger.2014.06.001

Simić-Krstić J, Kalauzi AJ, Ribar S, Matija L, Misević GN. Electrical properties of human skin as aging biomarkers. in Experimental Gerontology. 2014;57:163-167.
doi:10.1016/j.exger.2014.06.001 .

Simić-Krstić, Jovana, Kalauzi, Aleksandar J., Ribar, Srđan, Matija, Lidija, Misević, Gradimir N., "Electrical properties of human skin as aging biomarkers" in Experimental Gerontology, 57 (2014):163-167,
https://doi.org/10.1016/j.exger.2014.06.001 . .

TY  - JOUR
AU  - Vosika, Zoran B.
AU  - Lazović, Goran
AU  - Misević, Gradimir N.
AU  - Simić-Krstić, Jovana
PY  - 2013
UR  - https://machinery.mas.bg.ac.rs/handle/123456789/1679
AB  - Fractional calculus is a mathematical approach dealing with derivatives and integrals of arbitrary and complex orders. Therefore, it adds a new dimension to understand and describe basic nature and behavior of complex systems in an improved way. Here we use the fractional calculus for modeling electrical properties of biological systems. We derived a new class of generalized models for electrical impedance and applied them to human skin by experimental data fitting. The primary model introduces new generalizations of: 1) Weyl fractional derivative operator, 2) Cole equation, and 3) Constant Phase Element (CPE). These generalizations were described by the novel equation which presented parameter (beta) related to remnant memory and corrected four essential parameters (R-0, R-infinity, alpha, tau(alpha)). We further generalized single generalized element by introducing specific partial sum of Maclaurin series determined by parameters (beta(*), gamma,delta ...). We defined individual primary model elements and their serial combination models by the appropriate equations and electrical schemes. Cole equation is a special case of our generalized class of models for beta* = gamma = delta = ... = 0. Previous bioimpedance data analyses of living systems using basic Cole and serial Cole models show significant imprecisions. Our new class of models considerably improves the quality of fitting, evaluated by mean square errors, for bioimpedance data obtained from human skin. Our models with new parameters presented in specific partial sum of Maclaurin series also extend representation, understanding and description of complex systems electrical properties in terms of remnant memory effects.
PB  - Public Library Science, San Francisco
T2  - PLOS ONE
T1  - Fractional Calculus Model of Electrical Impedance Applied to Human Skin
IS  - 4
VL  - 8
DO  - 10.1371/journal.pone.0059483
ER  - 

@article{
author = "Vosika, Zoran B. and Lazović, Goran and Misević, Gradimir N. and Simić-Krstić, Jovana",
year = "2013",
abstract = "Fractional calculus is a mathematical approach dealing with derivatives and integrals of arbitrary and complex orders. Therefore, it adds a new dimension to understand and describe basic nature and behavior of complex systems in an improved way. Here we use the fractional calculus for modeling electrical properties of biological systems. We derived a new class of generalized models for electrical impedance and applied them to human skin by experimental data fitting. The primary model introduces new generalizations of: 1) Weyl fractional derivative operator, 2) Cole equation, and 3) Constant Phase Element (CPE). These generalizations were described by the novel equation which presented parameter (beta) related to remnant memory and corrected four essential parameters (R-0, R-infinity, alpha, tau(alpha)). We further generalized single generalized element by introducing specific partial sum of Maclaurin series determined by parameters (beta(*), gamma,delta ...). We defined individual primary model elements and their serial combination models by the appropriate equations and electrical schemes. Cole equation is a special case of our generalized class of models for beta* = gamma = delta = ... = 0. Previous bioimpedance data analyses of living systems using basic Cole and serial Cole models show significant imprecisions. Our new class of models considerably improves the quality of fitting, evaluated by mean square errors, for bioimpedance data obtained from human skin. Our models with new parameters presented in specific partial sum of Maclaurin series also extend representation, understanding and description of complex systems electrical properties in terms of remnant memory effects.",
publisher = "Public Library Science, San Francisco",
journal = "PLOS ONE",
title = "Fractional Calculus Model of Electrical Impedance Applied to Human Skin",
number = "4",
volume = "8",
doi = "10.1371/journal.pone.0059483"
}

Vosika, Z. B., Lazović, G., Misević, G. N.,& Simić-Krstić, J.. (2013). Fractional Calculus Model of Electrical Impedance Applied to Human Skin. in PLOS ONE
Public Library Science, San Francisco., 8(4).
https://doi.org/10.1371/journal.pone.0059483

Vosika ZB, Lazović G, Misević GN, Simić-Krstić J. Fractional Calculus Model of Electrical Impedance Applied to Human Skin. in PLOS ONE. 2013;8(4).
doi:10.1371/journal.pone.0059483 .

Vosika, Zoran B., Lazović, Goran, Misević, Gradimir N., Simić-Krstić, Jovana, "Fractional Calculus Model of Electrical Impedance Applied to Human Skin" in PLOS ONE, 8, no. 4 (2013),
https://doi.org/10.1371/journal.pone.0059483 . .